{"id":"W1980467489","doi":"10.1194/jlr.d008888","title":"Huh-7 or HepG2 cells: which is the better model for studying human apolipoprotein-B100 assembly and secretion?","year":2010,"lang":"en","type":"article","venue":"Journal of Lipid Research","topic":"Lipoproteins and Cardiovascular Health","field":"Medicine","cited_by":125,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"National Heart, Lung, and Blood Institute","keywords":"Secretion; Apolipoprotein B; Very low-density lipoprotein; Microsomal triglyceride transfer protein; Lipoprotein; Cell culture; Chemistry; Cell biology; Biochemistry; Endocrinology; Biology; Cholesterol","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0100648,0.000159441,0.0004901491,0.0002989549,0.0007131078,0.0001488058,0.0003131956,0.0001832333,0.0000953639],"category_scores_gemma":[0.0004250536,0.00008557865,0.0002785199,0.0003618021,0.0001506201,0.0001580169,0.0001296885,0.002047641,0.000006262171],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00008180011,"about_ca_system_score_gemma":0.0007327479,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001333209,"about_ca_topic_score_gemma":0.0001526184,"domain_scores_codex":[0.9965741,0.0002608628,0.0005721308,0.0002558084,0.00176346,0.0005736268],"domain_scores_gemma":[0.996854,0.000262939,0.000184552,0.0006076985,0.00172053,0.0003702799],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","study_design_scores_codex":[0.003157556,0.001167545,0.006254202,0.002558805,0.002014555,0.0001616704,0.009036806,0.00007688499,0.8311676,0.001009272,0.06400158,0.07939356],"study_design_scores_gemma":[0.05365166,0.02554757,0.07520164,0.003799923,0.002153685,0.007534009,0.01440788,0.1057003,0.2553802,0.01128073,0.4429429,0.00239955],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9766685,0.0003228933,0.0013343,0.01951283,0.000249921,0.001419306,0.000007415209,0.000009649422,0.0004752092],"genre_scores_gemma":[0.9888396,0.0002390716,0.003608121,0.0007341722,0.004738821,0.00007085643,0.000001562654,0.00004819743,0.00171962],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.5757874,"threshold_uncertainty_score":0.8896096,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1086989902485518,"score_gpt":0.4089490566576766,"score_spread":0.3002500664091248,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}