{"id":"W1980528148","doi":"10.1042/bj20081923","title":"Oxysterol activation of phosphatidylcholine synthesis involves CTP:phosphocholine cytidylyltransferase α translocation to the nuclear envelope","year":2008,"lang":"en","type":"article","venue":"Biochemical Journal","topic":"Cholesterol and Lipid Metabolism","field":"Medicine","cited_by":18,"is_retracted":false,"has_abstract":true,"ca_institutions":"Dalhousie University","funders":"","keywords":"Oxysterol; Phosphocholine; Phosphatidylcholine; Sphingomyelin; Chinese hamster ovary cell; Sterol; Choline; Sterol regulatory element-binding protein; Biochemistry; Biology; Chemistry; Molecular biology; Cholesterol; Phospholipid; Membrane","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001099161,0.0005062343,0.0002595158,0.0001524454,0.0001833529,0.0002973755,0.0001244799,0.0002008492,0.001223264],"category_scores_gemma":[0.0001012952,0.0001135338,0.0003697637,0.0001430675,0.0002669448,0.0002668475,0.0002596361,0.0003318666,0.0004177803],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004895971,"about_ca_system_score_gemma":0.000315611,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001472754,"about_ca_topic_score_gemma":0.002000602,"domain_scores_codex":[0.9998749,0.00001982663,0.00001191348,0.00003900546,0.00002592015,0.00002839795],"domain_scores_gemma":[0.9998778,0.00001711351,0.00002929744,0.00002317757,0.00002506007,0.00002751738],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001839755,0.00000733616,0.0002995112,0.00002796557,0.000005024606,0.00004896624,0.00001384161,0.00001677869,0.9983562,0.00005148662,0.000008562824,0.0009802999],"study_design_scores_gemma":[0.000008535653,0.0001127637,0.003431026,0.000003803115,0.00000750657,0.0001249812,0.00002773745,0.0001266678,0.9946399,0.00002619848,0.001488613,0.000002359179],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9862745,0.004297982,0.00636711,0.0001162359,0.0000522268,0.00007012647,0.0004836964,0.00007021373,0.002267963],"genre_scores_gemma":[0.9889904,0.002836224,0.002910653,0.0000471259,0.00001520766,0.00003984633,0.0008103129,0.00002028842,0.004329827],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001472754,"threshold_uncertainty_score":0.004092216,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02263360494816757,"score_gpt":0.2439330394107747,"score_spread":0.2212994344626071,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}