{"id":"W1980531623","doi":"10.1371/journal.pone.0030746","title":"Leishmania donovani: Immunostimulatory Cellular Responses of Membrane and Soluble Protein Fractions of Splenic Amastigotes in Cured Patient and Hamsters","year":2012,"lang":"en","type":"article","venue":"PLoS ONE","topic":"Research on Leishmaniasis Studies","field":"Medicine","cited_by":7,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université Laval","funders":"Council of Scientific and Industrial Research, India; Department of Biotechnology, Ministry of Science and Technology, India","keywords":"Visceral leishmaniasis; Leishmania donovani; Amastigote; Leishmania; Lymphoproliferative response; Leishmaniasis; Leishmania infantum; Biology; Immune system; Miltefosine; Canine leishmaniasis; Immunology; Immunity; Virology; Microbiology; Parasite hosting; In vitro; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001635587,0.0003586344,0.0002147237,0.0001430522,0.0001522672,0.000178265,0.00009620933,0.0002593276,0.002040665],"category_scores_gemma":[0.0001511032,0.000119231,0.0001932808,0.00007553168,0.0002009973,0.0001320992,0.0002077089,0.0005727207,0.0003853042],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001061128,"about_ca_system_score_gemma":0.00008472487,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002171648,"about_ca_topic_score_gemma":0.0002011777,"domain_scores_codex":[0.9999208,0.00001621332,0.000005836288,0.00001790551,0.00001180774,0.00002736918],"domain_scores_gemma":[0.9999357,0.0000179627,0.0000050814,0.00000850976,0.00001111062,0.00002156931],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0005894416,0.0001433329,0.000575314,0.000081636,0.000009425185,0.0001065144,0.00008147881,0.00004509521,0.9963477,0.000106579,0.00009196193,0.001821498],"study_design_scores_gemma":[0.0002635657,0.009984158,0.04193893,0.00004083195,0.00009591489,0.002085337,0.0002250277,0.001323434,0.9340577,0.0002352537,0.009732996,0.00001694607],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9964875,0.001446386,0.0005974965,0.00008512084,0.0000530032,0.00003934854,0.0002241399,0.00002601281,0.001040979],"genre_scores_gemma":[0.9948959,0.0008344033,0.0004958602,0.000120276,0.00003654994,0.00004495573,0.0007969021,0.000009742947,0.002765418],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002040665,"threshold_uncertainty_score":0.006826699,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05160179822242421,"score_gpt":0.268170437249311,"score_spread":0.2165686390268868,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}