{"id":"W1980581918","doi":"10.1016/j.cell.2009.03.026","title":"A Functional Screen to Identify Novel Effectors of Hematopoietic Stem Cell Activity","year":2009,"lang":"en","type":"article","venue":"Cell","topic":"Pluripotent Stem Cells Research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":129,"is_retracted":false,"has_abstract":false,"ca_institutions":"Université de Montréal; Institute for Research in Immunology and Cancer","funders":"Canadian Institutes of Health Research","keywords":"Biology; Stem cell; Haematopoiesis; Embryonic stem cell; Cell biology; Hematopoietic stem cell; Effector; Cell; Function (biology); Computational biology; Immunology; Gene; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002064226,0.0001423065,0.000163478,0.00007217278,0.00004579967,0.00001656486,0.0002220449,0.0001239423,0.00003507029],"category_scores_gemma":[0.000009592811,0.0001393175,0.0001183898,0.0001465463,0.00003377063,0.00000400045,0.0001213897,0.0001001165,0.00009003785],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002015955,"about_ca_system_score_gemma":0.00006047769,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001577777,"about_ca_topic_score_gemma":0.000003413213,"domain_scores_codex":[0.9988804,0.00005022657,0.0001535825,0.000353216,0.0002847782,0.0002777777],"domain_scores_gemma":[0.9993194,0.00002161043,0.00006429442,0.0003586588,0.00008470629,0.0001513419],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001237176,0.0002704934,0.0001875721,0.00006706557,0.0000102568,0.000002410955,0.00002010564,0.0001350134,0.995658,0.000003054891,0.002862461,0.000659786],"study_design_scores_gemma":[0.0005525435,0.0003911558,0.01662956,0.00001244816,0.00001032282,0.000004299525,0.00001660493,0.00003739934,0.9807827,0.000005130723,0.001418775,0.0001390159],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9860934,0.0001874588,0.008752758,0.00009457969,0.0000908757,0.0002904827,0.00002585721,0.00001033864,0.004454264],"genre_scores_gemma":[0.9948403,0.00001336741,0.0002566337,0.00008989366,0.00008472348,0.000008402793,0.00003199358,0.00001528624,0.004659452],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01644199,"threshold_uncertainty_score":0.5681203,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01863732611527529,"score_gpt":0.2777146009438443,"score_spread":0.259077274828569,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}