{"id":"W1980581918","doi":"10.1016/j.cell.2009.03.026","title":"A Functional Screen to Identify Novel Effectors of Hematopoietic Stem Cell Activity","year":2009,"lang":"en","type":"article","venue":"Cell","topic":"Pluripotent Stem Cells Research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":129,"is_retracted":false,"has_abstract":false,"ca_institutions":"Université de Montréal; Institute for Research in Immunology and Cancer","funders":"Canadian Institutes of Health Research","keywords":"Biology; Stem cell; Haematopoiesis; Embryonic stem cell; Cell biology; Hematopoietic stem cell; Effector; Cell; Function (biology); Computational biology; Immunology; Gene; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000359073,0.001081082,0.0005050732,0.0007393196,0.0004001184,0.000579145,0.0004699935,0.0005745159,0.004029503],"category_scores_gemma":[0.0002366082,0.0003344912,0.0005539472,0.0003797638,0.0004105569,0.000241877,0.0004637429,0.0008737039,0.001053057],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004252442,"about_ca_system_score_gemma":0.0003691338,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004444085,"about_ca_topic_score_gemma":0.0007816528,"domain_scores_codex":[0.9997099,0.00004383945,0.00003450558,0.00004615094,0.0001123613,0.00005318149],"domain_scores_gemma":[0.9997622,0.0001122595,0.0000360865,0.00002538169,0.00002017541,0.00004381813],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00007118697,0.00003545,0.0000980959,0.00002021732,0.000006301191,0.0001059086,0.000004773539,0.0000566316,0.9987055,0.0001483781,0.00003944018,0.0007081632],"study_design_scores_gemma":[0.00003288187,0.0002057718,0.001075735,0.000002717265,0.00003672817,0.0003422208,0.00001658211,0.0004329576,0.9961916,0.00004705356,0.001611212,0.000004469634],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9699141,0.001306757,0.01890573,0.0004277266,0.00009940859,0.0003381655,0.00300754,0.0005056113,0.005494864],"genre_scores_gemma":[0.9784709,0.0007989408,0.008470212,0.0002147433,0.00002090501,0.0001748263,0.003762568,0.0001263321,0.007960633],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.004029503,"threshold_uncertainty_score":0.01348007,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01863732611527529,"score_gpt":0.2777146009438443,"score_spread":0.259077274828569,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}