{"id":"W1980587036","doi":"10.1016/j.vaccine.2012.03.036","title":"BALB/c mice, but not C57BL/6 mice immunized with a ΔclpB mutant of Francisella tularensis subspecies tularensis are protected against respiratory challenge with wild-type bacteria: Association of protection with post-vaccination and post-challenge immune responses","year":2012,"lang":"en","type":"article","venue":"Vaccine","topic":"Bacillus and Francisella bacterial research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":52,"is_retracted":false,"has_abstract":false,"ca_institutions":"Institute for Biological Sciences; National Research Council Canada","funders":"National Institute of Allergy and Infectious Diseases; Vetenskapsrådet","keywords":"Francisella tularensis; Tularemia; Attenuated vaccine; Biology; Vaccination; Microbiology; Francisella; Virulence; Immune system; Virology; Immunology; Gene; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0008071394,0.0003971598,0.0006536192,0.0002572496,0.0001695577,0.00003402951,0.0001833312,0.0003823467,0.00003812866],"category_scores_gemma":[0.0004783398,0.0002976404,0.00007875772,0.0004550949,0.00005211884,0.00005538476,0.0001100157,0.0002784037,0.000002569284],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00008577346,"about_ca_system_score_gemma":0.0001847502,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002278817,"about_ca_topic_score_gemma":0.0006177999,"domain_scores_codex":[0.9975732,0.0004016057,0.0005425632,0.0005014663,0.0004831817,0.0004979966],"domain_scores_gemma":[0.9960008,0.00006889195,0.0007942063,0.0005641468,0.002436352,0.0001355828],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.02541288,0.0003326008,0.004756225,0.0003202626,0.0004119157,0.000006244999,0.000441986,0.00000443826,0.9658681,0.000006893746,0.000006640808,0.002431834],"study_design_scores_gemma":[0.004153239,0.004259233,0.272706,0.0002058697,0.0001144995,0.00002334014,0.0004592882,0.00001119673,0.7169691,0.00000123132,0.0007469155,0.0003501236],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9951051,0.002501376,0.0001214798,0.0005039581,0.00007082694,0.001432899,0.0001719568,0.00002906538,0.00006336983],"genre_scores_gemma":[0.9976969,0.001044601,0.0006032646,0.00004728487,0.0001505402,0.00009901044,0.0001627759,0.00007911665,0.0001164769],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2679498,"threshold_uncertainty_score":0.9999475,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01294818744622606,"score_gpt":0.2246650817872383,"score_spread":0.2117168943410122,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}