{"id":"W1980587036","doi":"10.1016/j.vaccine.2012.03.036","title":"BALB/c mice, but not C57BL/6 mice immunized with a ΔclpB mutant of Francisella tularensis subspecies tularensis are protected against respiratory challenge with wild-type bacteria: Association of protection with post-vaccination and post-challenge immune responses","year":2012,"lang":"en","type":"article","venue":"Vaccine","topic":"Bacillus and Francisella bacterial research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":52,"is_retracted":false,"has_abstract":false,"ca_institutions":"Institute for Biological Sciences; National Research Council Canada","funders":"National Institute of Allergy and Infectious Diseases; Vetenskapsrådet","keywords":"Francisella tularensis; Tularemia; Attenuated vaccine; Biology; Vaccination; Microbiology; Francisella; Virulence; Immune system; Virology; Immunology; Gene; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000411339,0.00174053,0.001026791,0.001460662,0.0004077505,0.0006789607,0.000717554,0.00156196,0.004358492],"category_scores_gemma":[0.000317004,0.0005943618,0.0007209717,0.0003553283,0.000784836,0.0008370632,0.000328745,0.00311186,0.001524061],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004469761,"about_ca_system_score_gemma":0.0004255129,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001110618,"about_ca_topic_score_gemma":0.00152841,"domain_scores_codex":[0.9994136,0.000050506,0.00004323353,0.0001587101,0.0001071719,0.0002267488],"domain_scores_gemma":[0.9988747,0.0001279446,0.0003624219,0.000141636,0.00008934677,0.0004038706],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001056166,0.0002959758,0.0003165781,0.00005190607,0.00001505723,0.00005213587,0.00003215078,0.00004285902,0.9974216,0.00009012722,0.00007612176,0.000549281],"study_design_scores_gemma":[0.0002195299,0.002893317,0.01506387,0.00003677933,0.00009277379,0.0006124124,0.0001326386,0.000756947,0.978387,0.0002111653,0.001564526,0.00002912869],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9921877,0.001144194,0.002153658,0.0003995321,0.000228331,0.00008857286,0.001793585,0.0003139923,0.001690421],"genre_scores_gemma":[0.9795293,0.001049883,0.002712775,0.0004300092,0.00009312282,0.0001817631,0.002571732,0.0001634166,0.01326802],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.004358492,"threshold_uncertainty_score":0.01458061,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01294818744622606,"score_gpt":0.2246650817872383,"score_spread":0.2117168943410122,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}