{"id":"W1980599602","doi":"10.1039/b803281e","title":"Towards sequence selective DNA binding: design, synthesis and DNA binding studies of novel bis-porphyrin peptidic nanostructures","year":2008,"lang":"en","type":"article","venue":"Organic & Biomolecular Chemistry","topic":"DNA and Nucleic Acid Chemistry","field":"Biochemistry, Genetics and Molecular Biology","cited_by":21,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université Laval","funders":"Natural Sciences and Engineering Research Council of Canada; Fonds Québécois de la Recherche sur la Nature et les Technologies","keywords":"Circular dichroism; Chemistry; Porphyrin; Intercalation (chemistry); Cationic polymerization; DNA; Sequence (biology); Stereochemistry; Peptide; Combinatorial chemistry; Crystallography; Polymer chemistry; Photochemistry; Biochemistry; Organic chemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001407465,0.0002611295,0.0002429295,0.0001007857,0.0001238275,0.0002158152,0.0002383514,0.0003234608,0.0003442762],"category_scores_gemma":[0.0002120333,0.0001899006,0.0001053301,0.00008508516,0.0001582614,0.0001620004,0.0001192793,0.0002894049,0.0001945234],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002390342,"about_ca_system_score_gemma":0.0001385986,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004086533,"about_ca_topic_score_gemma":0.0006024482,"domain_scores_codex":[0.9998934,0.00001954356,0.000006585382,0.0000308599,0.00003405487,0.00001549803],"domain_scores_gemma":[0.9999086,0.00001915948,0.0000233367,0.00000584388,0.00001848169,0.00002463103],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000009366909,0.000007790155,0.0000227075,0.0000208501,0.000001009368,0.00001125207,0.000006439212,0.00008180204,0.9992315,0.00002010199,0.000005432454,0.0005818257],"study_design_scores_gemma":[0.00000442859,0.0000849823,0.0002632337,0.000001458454,0.000003376427,0.0001013118,0.000003720735,0.0006743221,0.9982349,0.00001161222,0.0006146829,0.000001981105],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9793079,0.00208239,0.01703263,0.00009953141,0.00001892201,0.00007260211,0.0001209914,0.00009405443,0.001170962],"genre_scores_gemma":[0.9706114,0.001048877,0.02647798,0.0000807517,0.000009152683,0.00004814088,0.0001911962,0.00002182941,0.001510608],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0004086533,"threshold_uncertainty_score":0.001734316,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02947369005512508,"score_gpt":0.2612955153297327,"score_spread":0.2318218252746076,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}