{"id":"W1980651659","doi":"10.1074/jbc.m308423200","title":"Overexpression of l-Isoaspartate O-Methyltransferase in Escherichia coli Increases Heat Shock Survival by a Mechanism Independent of Methyltransferase Activity","year":2003,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"Enzyme Structure and Function","field":"Materials Science","cited_by":40,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Saskatchewan","funders":"","keywords":"Methyltransferase; Mechanism (biology); Escherichia coli; Shock (circulatory); Chemistry; Medicine; Biochemistry; Internal medicine; Methylation; Physics; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001276033,0.0003207438,0.0001815759,0.0001920967,0.0000766067,0.0003247265,0.000194639,0.0002388255,0.0005644412],"category_scores_gemma":[0.0001580179,0.0001310032,0.0002542696,0.000171703,0.0001841972,0.0001514229,0.0002300463,0.0004580283,0.0002730315],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002805569,"about_ca_system_score_gemma":0.0001704772,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000542779,"about_ca_topic_score_gemma":0.0005686523,"domain_scores_codex":[0.9998608,0.00002344086,0.00002261421,0.00002425364,0.00003591036,0.00003305527],"domain_scores_gemma":[0.999814,0.00003727309,0.00005913597,0.00003474999,0.00001655841,0.00003837877],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00005711417,0.00002631684,0.0001731469,0.00001108928,0.000003708632,0.0000206604,0.000005125086,0.0000419821,0.999143,0.00003996573,0.000007997704,0.0004698074],"study_design_scores_gemma":[0.00000528593,0.0001583915,0.002385919,0.00000309409,0.000008556314,0.00007863086,0.0000124278,0.0005990895,0.9961786,0.00001828865,0.0005483524,0.000003287807],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9960694,0.0003778117,0.002507686,0.000085878,0.00001652952,0.00002116349,0.0002259742,0.00009425478,0.0006013334],"genre_scores_gemma":[0.993468,0.0003369308,0.004221211,0.00003654032,0.000005519079,0.00001793488,0.0004427301,0.00002258866,0.001448538],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0005644412,"threshold_uncertainty_score":0.002035618,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01759837294783424,"score_gpt":0.2490392894363736,"score_spread":0.2314409164885393,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}