{"id":"W1980654996","doi":"10.1038/mp.2014.42","title":"Ankyrin-G regulates neurogenesis and Wnt signaling by altering the subcellular localization of β-catenin","year":2014,"lang":"en","type":"article","venue":"Molecular Psychiatry","topic":"Genetics and Neurodevelopmental Disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":64,"is_retracted":false,"has_abstract":false,"ca_institutions":"McMaster University","funders":"National Institute of Mental Health; Howard Hughes Medical Institute","keywords":"Ankyrin; Wnt signaling pathway; Biology; Neurogenesis; Cell biology; Ankyrin repeat; Catenin; Neuroscience; Neural stem cell; Progenitor cell; Signal transduction; Genetics; Gene; Stem cell","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000136186,0.0001282505,0.0001029114,0.00003396027,0.00005026206,0.0000150455,0.0001342359,0.00005531569,0.000002646466],"category_scores_gemma":[0.00001449586,0.0001130801,0.00004494064,0.000100995,0.00006169861,0.000001757414,0.0000780682,0.00004364389,6.979639e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000002434719,"about_ca_system_score_gemma":0.00001757643,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001668889,"about_ca_topic_score_gemma":0.00001541905,"domain_scores_codex":[0.9991757,0.00007847862,0.0002062579,0.0002798178,0.00010013,0.000159559],"domain_scores_gemma":[0.9996762,0.000004812382,0.00006617316,0.0001944222,0.00002085332,0.0000374939],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00001656644,0.00003286833,0.01259491,0.00003031337,0.00001404549,5.075022e-7,0.00002187544,0.002087734,0.9843552,0.0001103648,0.0001082829,0.0006273496],"study_design_scores_gemma":[0.0004170977,0.0001343242,0.009330765,0.00001995287,0.00001527429,0.000008139712,0.00004807189,0.001482364,0.9863502,0.0004353812,0.001583054,0.0001753941],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.987264,0.002879277,0.009295672,0.0002530088,0.0001020831,0.0001213113,0.000002288322,0.000004577389,0.00007779174],"genre_scores_gemma":[0.9987549,0.0001829651,0.0005228669,0.0004479101,0.000009969379,0.000008615685,0.00002913957,0.00002562051,0.00001805696],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01149087,"threshold_uncertainty_score":0.4611272,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.002774325371809403,"score_gpt":0.1824520835481974,"score_spread":0.179677758176388,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}