{"id":"W1980669919","doi":"10.1371/journal.pone.0026248","title":"Biochemical and Computational Analysis Of LNX1 Interacting Proteins","year":2011,"lang":"en","type":"article","venue":"PLoS ONE","topic":"Hippo pathway signaling and YAP/TAZ","field":"Biochemistry, Genetics and Molecular Biology","cited_by":24,"is_retracted":false,"has_abstract":true,"ca_institutions":"Hospital for Sick Children; SickKids Foundation; University of Toronto","funders":"National Cancer Institute; Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research; Terry Fox Foundation","keywords":"PDZ domain; Scaffold protein; Ubiquitin ligase; Transmembrane protein; Protein–protein interaction; Biology; Plasma protein binding; Computational biology; Cell biology; Biochemistry; Ubiquitin; Signal transduction; Gene; Receptor","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003529174,0.000832202,0.0007752414,0.0009007251,0.0008651266,0.0007470053,0.0009182167,0.0006986317,0.00376472],"category_scores_gemma":[0.0009015583,0.0004053173,0.001080192,0.0008369476,0.0002543171,0.000377154,0.0003242306,0.0004759589,0.0008708046],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000970171,"about_ca_system_score_gemma":0.00106814,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.008934813,"about_ca_topic_score_gemma":0.01065966,"domain_scores_codex":[0.9998689,0.00002477127,0.000008588329,0.00004399789,0.00002873088,0.00002507228],"domain_scores_gemma":[0.9997578,0.0001401155,0.00002379309,0.00001721912,0.00003152262,0.00002951554],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"simulation_or_modeling","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001131574,0.0007516002,0.02364264,0.0007420967,0.000471019,0.001058857,0.0001501888,0.9149915,0.02095877,0.007397709,0.007569996,0.02113404],"study_design_scores_gemma":[0.00004550704,0.00002799482,0.003303588,0.000003292463,0.00002677646,0.00004618983,0.00003378373,0.993393,0.001232591,0.0009721362,0.0009081212,0.000006886331],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9729226,0.0005369927,0.01076077,0.000408701,0.00003296904,0.00007420609,0.006642773,0.002689074,0.005931821],"genre_scores_gemma":[0.9378619,0.0005569183,0.03725132,0.0001143526,0.00002046091,0.0002233828,0.02184437,0.000239548,0.001887752],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.008934813,"threshold_uncertainty_score":0.01776564,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05013799727734673,"score_gpt":0.2385768616119811,"score_spread":0.1884388643346344,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}