{"id":"W1980690811","doi":"10.3899/jrheum.131238","title":"When to Adjust Therapy in Patients with Rheumatoid Arthritis After Initiation of Etanercept plus Methotrexate or Methotrexate Alone: Findings from a Randomized Study (COMET)","year":2014,"lang":"en","type":"article","venue":"The Journal of Rheumatology","topic":"Rheumatoid Arthritis Research and Therapies","field":"Medicine","cited_by":10,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Sanofi; GlaxoSmithKline; Chugai Pharmaceutical; Amgen; Pfizer; AstraZeneca; Eli Lilly and Company; Bristol-Myers Squibb","keywords":"Medicine; Etanercept; Methotrexate; Erythrocyte sedimentation rate; Rheumatoid arthritis; Internal medicine; Gastroenterology; Combination therapy; Arthritis; Surgery","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":true,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.006529718,0.0005985709,0.003302874,0.0003754547,0.0004614406,0.001183846,0.0005208391,0.002130041,0.002075061],"category_scores_gemma":[0.01131609,0.0004530488,0.003291734,0.0004022416,0.0006510066,0.001031761,0.0003323168,0.001639062,0.0003861231],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004159142,"about_ca_system_score_gemma":0.0007432469,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004513655,"about_ca_topic_score_gemma":0.0008108446,"domain_scores_codex":[0.9952652,0.003045337,0.0006175668,0.0005183573,0.0003566772,0.0001968609],"domain_scores_gemma":[0.9916476,0.004679794,0.002077425,0.000568591,0.0002812763,0.0007454568],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9225639,0.005378678,0.01564826,0.0008759947,0.006338097,0.00005032528,0.0001149058,0.0003434232,0.001184408,0.00007239014,0.0007636861,0.04666605],"study_design_scores_gemma":[0.8399985,0.1210283,0.02958487,0.0001963906,0.005754359,0.0001165939,0.00007724307,0.001139137,0.0006309153,0.0002165371,0.001223422,0.00003375701],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9807279,0.01401121,0.0007174005,0.001457214,0.0009130753,0.0009367531,0.0002819903,0.00006146011,0.0008929615],"genre_scores_gemma":[0.9945774,0.001474633,0.000943046,0.001241532,0.0005941427,0.0006951477,0.0002052278,0.000009141906,0.0002598116],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.006529718,"threshold_uncertainty_score":0.03453285,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01657701379001007,"score_gpt":0.2788096376190747,"score_spread":0.2622326238290646,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}