{"id":"W1980740451","doi":"10.1016/j.cell.2007.05.047","title":"Endocrine Regulation of Energy Metabolism by the Skeleton","year":2007,"lang":"en","type":"article","venue":"Cell","topic":"Protein Tyrosine Phosphatases","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2541,"is_retracted":false,"has_abstract":false,"ca_institutions":"McGill University","funders":"National Institute of Arthritis and Musculoskeletal and Skin Diseases; Eunice Kennedy Shriver National Institute of Child Health and Human Development; National Institute of Diabetes and Digestive and Kidney Diseases; Pennsylvania Department of Health; American Diabetes Association","keywords":"Biology; Osteocalcin; Endocrinology; Internal medicine; Glucose homeostasis; Insulin resistance; Bone remodeling; Insulin; Carbohydrate metabolism; Energy homeostasis; Adiponectin; Insulin receptor; Adipokine; Adipose tissue; Glucose uptake; Alkaline phosphatase; Biochemistry; Medicine; Obesity","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001522879,0.0003121027,0.0002049111,0.0004806128,0.000297718,0.0006405507,0.0002405438,0.0003200699,0.001725759],"category_scores_gemma":[0.0001654266,0.0002066602,0.0002307248,0.0003506127,0.0006053979,0.0005785159,0.0004809833,0.0005441116,0.0004300386],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006158397,"about_ca_system_score_gemma":0.0003246397,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001408071,"about_ca_topic_score_gemma":0.003244919,"domain_scores_codex":[0.9999197,0.00001478393,0.000004123989,0.00001675146,0.00002312381,0.0000214515],"domain_scores_gemma":[0.9998969,0.00001880966,0.00002171242,0.00001191929,0.0000181244,0.00003256564],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0006429225,0.00003184523,0.001419407,0.0000988325,0.00002539764,0.0004604946,0.00004020428,0.000365316,0.9687833,0.009077055,0.0009299009,0.01812537],"study_design_scores_gemma":[0.0002305274,0.0004995402,0.06644095,0.00004602662,0.0000944196,0.002432964,0.0003336985,0.003806466,0.8668895,0.01104661,0.04812638,0.00005283449],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.8790359,0.06045317,0.02625441,0.003902463,0.0004367222,0.00004620549,0.0007953306,0.0002916306,0.02878416],"genre_scores_gemma":[0.9610922,0.01785376,0.004608047,0.0002004565,0.00008507425,0.00001708801,0.0003123795,0.00004736157,0.01578365],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001725759,"threshold_uncertainty_score":0.005773246,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.004007319868877987,"score_gpt":0.2127747066079078,"score_spread":0.2087673867390299,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}