{"id":"W1980813169","doi":"10.1080/14756360310001624975","title":"Cytotoxic and Topographical Properties of 6-Arylidene-2-dimethylaminomethylcyclohexanone Hydrochlorides and Related Compounds","year":2004,"lang":"en","type":"article","venue":"Journal of Enzyme Inhibition and Medicinal Chemistry","topic":"Synthesis and biological activity","field":"Chemistry","cited_by":13,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Saskatchewan","funders":"","keywords":"Cytotoxicity; Chemistry; L1210 cells; Stereochemistry; Cytotoxic T cell; Cell culture; Mannich reaction; Aryl; Biochemistry; In vitro; Organic chemistry; Biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003749498,0.0001609891,0.0004221344,0.00005174277,0.00006821867,0.00001865006,0.00005265034,0.0002115863,0.00008723628],"category_scores_gemma":[0.0002753069,0.000107996,0.00008017031,0.00009063857,0.0005876542,0.0001143153,0.00004792647,0.0003789216,1.274766e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002789801,"about_ca_system_score_gemma":0.00004097599,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001219002,"about_ca_topic_score_gemma":9.363368e-7,"domain_scores_codex":[0.9988984,0.00001728028,0.0005140876,0.0001729806,0.0002529103,0.0001443246],"domain_scores_gemma":[0.9991613,0.0001110667,0.0003577045,0.0000775458,0.00009570888,0.0001966657],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001903995,0.0001413174,0.001323719,0.000352321,0.00005280162,0.00004795279,0.000111958,6.762334e-7,0.9968751,0.00002426814,0.00001034239,0.0008691337],"study_design_scores_gemma":[0.001375173,0.0001506844,0.002159182,0.0008445845,0.00007426377,0.001778509,0.0005943957,0.000004709117,0.9914258,0.001368713,0.00009670876,0.0001272579],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9929002,0.005373844,0.000008930208,0.0006543247,0.00002396296,0.00002577807,0.000004439229,0.00001068672,0.0009978254],"genre_scores_gemma":[0.9982923,0.001339775,0.0001075394,0.00004545215,0.0001510045,0.000001596522,0.000002209213,0.000007315178,0.0000527699],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.005449291,"threshold_uncertainty_score":0.4403948,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01473039548903411,"score_gpt":0.2163620841216082,"score_spread":0.2016316886325741,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}