{"id":"W1980831097","doi":"10.1002/jcb.21102","title":"Calcium signaling in nonâexcitable cells: Ca2+release and influx are independent events linked to two plasma membrane Ca2+entry channels","year":2006,"lang":"en","type":"review","venue":"Journal of Cellular Biochemistry","topic":"Ion Channels and Receptors","field":"Neuroscience","cited_by":44,"is_retracted":false,"has_abstract":true,"ca_institutions":"St. Michael's Hospital","funders":"","keywords":"Extracellular; Cytosol; TRPC; Intracellular; Chemistry; Calcium; Biophysics; Cell biology; Calcium signaling; ORAI1; Voltage-dependent calcium channel; Transient receptor potential channel; Biochemistry; Biology; Receptor; Enzyme","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003767808,0.0004691357,0.0007140267,0.0003213609,0.0003713681,0.001104824,0.0008212332,0.001066845,0.001640097],"category_scores_gemma":[0.0003810783,0.0001744241,0.0006214728,0.0004795755,0.0006828613,0.001919455,0.000558374,0.0008794335,0.0004083311],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005115129,"about_ca_system_score_gemma":0.0003960355,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004711986,"about_ca_topic_score_gemma":0.0004988755,"domain_scores_codex":[0.9995511,0.00004197667,0.00004830144,0.0001094268,0.0001585918,0.00009064469],"domain_scores_gemma":[0.9997513,0.00005575315,0.00007420774,0.00003886893,0.00004303186,0.00003685621],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0002676093,0.00001992615,0.0003730425,0.0003829057,0.00001423205,0.0004063451,0.000042051,0.00006069219,0.994491,0.0008720547,0.00007394721,0.002996314],"study_design_scores_gemma":[0.00008392351,0.0004114983,0.02004703,0.00006046318,0.00009122764,0.001800505,0.0001284688,0.002827002,0.9652116,0.002356962,0.006943617,0.00003765643],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"review","genre_scores_codex":[0.893927,0.04049526,0.05220893,0.001801366,0.0004266944,0.0002467858,0.001171544,0.0005100516,0.009212334],"genre_scores_gemma":[0.9798405,0.007940939,0.008373146,0.0004846018,0.0001268956,0.0001614689,0.00056502,0.00004137217,0.002466199],"genre_candidate":"review","genre_consensus":null,"teacher_disagreement_score":0.001640097,"threshold_uncertainty_score":0.005486727,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0277825992567443,"score_gpt":0.2817787259186689,"score_spread":0.2539961266619246,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}