{"id":"W1980904413","doi":"10.1006/bbrc.2001.5536","title":"Differential Effects of Filipin and Methyl-β-cyclodextrin on B Cell Receptor Signaling","year":2001,"lang":"en","type":"article","venue":"Biochemical and Biophysical Research Communications","topic":"Lipid Membrane Structure and Behavior","field":"Biochemistry, Genetics and Molecular Biology","cited_by":75,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Calgary","funders":"","keywords":"Filipin; Lipid raft; Signal transduction; Cell biology; Chemistry; Phosphorylation; Calcium; Cyclodextrin; Receptor; Biochemistry; Biophysics; Biology; Cholesterol","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002800446,0.0003154414,0.0004150821,0.0002699698,0.0002917261,0.000599299,0.0002866201,0.0005253181,0.001808078],"category_scores_gemma":[0.0005000717,0.0002667834,0.0002833607,0.0002835433,0.0005687355,0.0004666948,0.0003012895,0.000736571,0.0003069706],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006405431,"about_ca_system_score_gemma":0.0004055423,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001039758,"about_ca_topic_score_gemma":0.001281978,"domain_scores_codex":[0.9996221,0.00006588158,0.00002913964,0.00003635961,0.00005690841,0.0001894301],"domain_scores_gemma":[0.9995875,0.0001959411,0.00003546263,0.00003912529,0.00002692052,0.0001150113],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00165893,0.00005799056,0.0001960037,0.00003168071,0.000008402057,0.000076352,0.00001619398,0.00008789201,0.9969317,0.0001406332,0.00002571942,0.0007684103],"study_design_scores_gemma":[0.00006443522,0.0002554667,0.004198286,0.000003263673,0.00001911941,0.0001328922,0.0000520134,0.0003640901,0.9944088,0.00004181969,0.0004540777,0.000005670534],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9981579,0.0007239908,0.0001921156,0.00006441272,0.00002299404,0.00000594873,0.000106508,0.00001035897,0.0007157151],"genre_scores_gemma":[0.9982238,0.0004702887,0.0002960639,0.00006007702,0.00001511546,0.00001152369,0.0001379029,0.000007039001,0.0007781328],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001808078,"threshold_uncertainty_score":0.00604862,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03175322528930683,"score_gpt":0.3356972101261405,"score_spread":0.3039439848368336,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}