{"id":"W1980932234","doi":"10.1152/ajpcell.00192.2002","title":"High glucose-induced, endothelin-dependent fibronectin synthesis is mediated via NF-κB and AP-1","year":2003,"lang":"en","type":"article","venue":"American Journal of Physiology-Cell Physiology","topic":"Cell Adhesion Molecules Research","field":"Medicine","cited_by":132,"is_retracted":false,"has_abstract":true,"ca_institutions":"Western University","funders":"","keywords":"Endothelin 1; Protein kinase C; NF-κB; Fibronectin; Downregulation and upregulation; Signal transduction; Cell biology; Chemistry; Receptor; NFKB1; Transcription factor; Molecular biology; Biology; Biochemistry; Gene; Extracellular matrix","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001054118,0.0003278858,0.00009289737,0.0001535357,0.0001081476,0.0002125646,0.0001056136,0.00009888278,0.001252008],"category_scores_gemma":[0.00008724546,0.00008837183,0.0001599357,0.0001250738,0.0001222615,0.0001195762,0.0001132718,0.0002850528,0.0001794894],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002327225,"about_ca_system_score_gemma":0.0001245393,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008852581,"about_ca_topic_score_gemma":0.001116517,"domain_scores_codex":[0.9998987,0.000017148,0.000009923589,0.00001842693,0.00003192508,0.00002390156],"domain_scores_gemma":[0.9999329,0.00001187219,0.00002021279,0.000007945907,0.00001197744,0.00001505934],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001051401,0.00001597705,0.0002483088,0.00005250046,0.000004814995,0.00008373116,0.00001263869,0.0000169007,0.9978966,0.00005454584,0.00002283777,0.001486034],"study_design_scores_gemma":[0.0000288435,0.0002436052,0.02809229,0.00001583188,0.00002846669,0.0005679704,0.00005345843,0.0005771854,0.9674665,0.0001018746,0.002818956,0.000005109704],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9857417,0.006567519,0.004632096,0.0001250771,0.00006919841,0.00002434229,0.0003688784,0.00004159876,0.002429537],"genre_scores_gemma":[0.9912226,0.002857244,0.002241371,0.00004625068,0.00002432665,0.00003279849,0.000491121,0.000005015604,0.003079255],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001252008,"threshold_uncertainty_score":0.004188359,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01125805298007287,"score_gpt":0.263020329237141,"score_spread":0.2517622762570682,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}