{"id":"W1980950441","doi":"10.1158/1538-7445.am2012-1686","title":"Abstract 1686: Identification of potential prostate cancer biomarkers associated with TMPRSS2-ERG fusion and PTEN deletions","year":2012,"lang":"en","type":"article","venue":"Cancer Research","topic":"Prostate Cancer Treatment and Research","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Calgary","funders":"","keywords":"TMPRSS2; PTEN; DU145; Fusion gene; Biology; Prostate cancer; Erg; Cancer research; Gene knockdown; Molecular biology; Gene; LNCaP; Cancer; Genetics; Medicine; Pathology; PI3K/AKT/mTOR pathway; Signal transduction","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001283321,0.0003398798,0.000279104,0.001102443,0.0001518942,0.0003631331,0.0001333405,0.0003105249,0.002066225],"category_scores_gemma":[0.0002254133,0.00009932269,0.0002133177,0.0007842463,0.0001077926,0.0001294853,0.0001487973,0.0002489041,0.0005799754],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001359022,"about_ca_system_score_gemma":0.0001773275,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003262808,"about_ca_topic_score_gemma":0.0003639662,"domain_scores_codex":[0.9999,0.00001102283,0.000008250637,0.00002311654,0.00003824972,0.00001939553],"domain_scores_gemma":[0.9998758,0.00002298593,0.00004000389,0.000005631898,0.00002714404,0.00002837344],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001465503,0.0001742304,0.1697958,0.0003939621,0.0001066226,0.001347564,0.00007122116,0.0003271281,0.8055714,0.0001063524,0.001255555,0.01938458],"study_design_scores_gemma":[0.00004032451,0.0009186923,0.7401121,0.00003228219,0.0001850639,0.008003431,0.0002190979,0.002642098,0.2426313,0.0002410082,0.004953424,0.00002118958],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9955245,0.00129228,0.0007129403,0.00008634077,0.00001689211,0.00002011493,0.001764162,0.00004525052,0.0005376357],"genre_scores_gemma":[0.9912751,0.0004634696,0.002283855,0.00005261103,0.00002564533,0.00002657206,0.004553001,0.000008508806,0.001311379],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002066225,"threshold_uncertainty_score":0.006912231,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05890981685796283,"score_gpt":0.4041013279733595,"score_spread":0.3451915111153967,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}