{"id":"W1981010107","doi":"10.1189/jlb.1008585","title":"HMGB1 loves company","year":2009,"lang":"en","type":"review","venue":"Journal of Leukocyte Biology","topic":"Advanced Glycation End Products research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":411,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Associazione Italiana per la Ricerca sul Cancro; Ministry of Health, British Columbia; Fondazione Cariplo; European Commission","keywords":"HMGB1; Biology; Inflammation; TLR2; Cell biology; Proinflammatory cytokine; Innate immune system; TLR4; Receptor; Stimulus (psychology); Immunology; Chemotaxis; Immune system; Genetics","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005227674,0.0008040649,0.0007380733,0.001168553,0.0005331537,0.001251379,0.000847747,0.002216556,0.01829433],"category_scores_gemma":[0.0009932815,0.0003014492,0.0003332394,0.0009455475,0.0006501746,0.002126555,0.001007645,0.003080798,0.01926407],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007654837,"about_ca_system_score_gemma":0.0007937715,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001101123,"about_ca_topic_score_gemma":0.002357261,"domain_scores_codex":[0.9996808,0.00004673047,0.00002991481,0.00005233475,0.0001597208,0.00003060809],"domain_scores_gemma":[0.999675,0.00009658856,0.00004131334,0.00001744832,0.0001044402,0.00006524355],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0000782556,0.00004415951,0.0001287486,0.002509082,0.00002937346,0.0002208845,0.00007851102,0.00006393417,0.001159946,0.006683288,0.2490125,0.7399913],"study_design_scores_gemma":[0.000005969904,0.00001382956,0.00009703042,0.0002625647,0.000005083327,0.0003465897,0.00001201589,0.000006673387,0.000093266,0.0004728119,0.9986812,0.000002985844],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0001855436,0.9656146,0.0003435521,0.007269882,0.007217817,0.00002436729,0.00004672801,0.00004840951,0.01924913],"genre_scores_gemma":[0.001995994,0.9212451,0.0009929719,0.01076294,0.004711446,0.00003728188,0.0001293746,0.00002726901,0.06009769],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.01829433,"threshold_uncertainty_score":0.06120062,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.06421898840395734,"score_gpt":0.4177893635178112,"score_spread":0.3535703751138539,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}