{"id":"W1981033235","doi":"10.2147/tcrm.s50170","title":"New treatments for genotype 1 chronic hepatitis C – focus on simeprevir","year":2014,"lang":"en","type":"review","venue":"Therapeutics and Clinical Risk Management","topic":"Hepatitis C virus research","field":"Medicine","cited_by":20,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"","keywords":"Simeprevir; Ribavirin; Medicine; Internal medicine; Hepatitis C virus; Hepatocellular carcinoma; Virology; Gastroenterology; Virus","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003224267,0.0007167462,0.001073818,0.002237801,0.0002362989,0.0006028075,0.000544206,0.0006268952,0.006749285],"category_scores_gemma":[0.0004277609,0.0001681268,0.0006400754,0.002048478,0.0002980576,0.0008116845,0.000498443,0.001358397,0.002518857],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003733311,"about_ca_system_score_gemma":0.0007457258,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009571362,"about_ca_topic_score_gemma":0.002240305,"domain_scores_codex":[0.9998649,0.00002324333,0.00002171779,0.00002466933,0.00005301179,0.00001234517],"domain_scores_gemma":[0.9998367,0.00007194756,0.00003091155,0.000005581668,0.00003834382,0.00001646773],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00007898793,0.00006554646,0.0001160125,0.02265576,0.0001113003,0.0001171212,0.00004299293,0.0001311105,0.001735418,0.001704736,0.0237039,0.9495372],"study_design_scores_gemma":[0.00004149445,0.0001095482,0.001120094,0.007106761,0.0003004613,0.001320229,0.00005138605,0.00006534732,0.0005654067,0.001017258,0.988289,0.00001307557],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0001343097,0.9981305,0.00007601011,0.0001663282,0.0001351189,0.000007815821,0.00002345895,0.000006983809,0.001319409],"genre_scores_gemma":[0.0008363166,0.9976875,0.0001852525,0.0002280001,0.0001061287,0.00000800753,0.00003875878,0.000001538682,0.0009085805],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.006749285,"threshold_uncertainty_score":0.02257854,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1734346742697351,"score_gpt":0.4912994549808696,"score_spread":0.3178647807111346,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}