{"id":"W1981033235","doi":"10.2147/tcrm.s50170","title":"New treatments for genotype 1 chronic hepatitis C – focus on simeprevir","year":2014,"lang":"en","type":"review","venue":"Therapeutics and Clinical Risk Management","topic":"Hepatitis C virus research","field":"Medicine","cited_by":20,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"","keywords":"Simeprevir; Ribavirin; Medicine; Internal medicine; Hepatitis C virus; Hepatocellular carcinoma; Virology; Gastroenterology; Virus","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.001173437,0.0006098977,0.002449629,0.0002028836,0.0001587127,0.00008109304,0.0003290434,0.0004678059,0.0003281568],"category_scores_gemma":[0.00009660018,0.000440121,0.001009231,0.0002066862,0.0001131716,0.00002356919,0.0002209216,0.0007285281,0.001098877],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003692546,"about_ca_system_score_gemma":0.0002822113,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000232864,"about_ca_topic_score_gemma":0.0002612596,"domain_scores_codex":[0.9961144,0.0004477927,0.001319931,0.0009568233,0.0005405612,0.0006205275],"domain_scores_gemma":[0.9966252,0.001168684,0.0004737827,0.001200187,0.00007073136,0.0004614275],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001095842,0.0002971794,0.0003877394,0.00468095,0.00492496,0.00001178531,0.000007270843,2.255369e-7,1.033943e-8,0.0008844832,0.002374326,0.9863215],"study_design_scores_gemma":[0.002512952,0.003662797,0.0004012508,0.004458799,0.0120713,0.000001596318,7.185878e-7,0.00007349048,1.165844e-7,0.001454837,0.9749939,0.0003682828],"study_design_candidate":"design_other","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.00002023341,0.9833825,0.003774014,0.0002105162,0.000312734,0.005054185,0.0001292506,0.00007260156,0.007043988],"genre_scores_gemma":[0.00002726702,0.9807732,0.003073122,0.0004217238,0.0009157809,0.0003050157,0.0002107987,0.000155203,0.01411797],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9859532,"threshold_uncertainty_score":0.999805,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1734346742697351,"score_gpt":0.4912994549808696,"score_spread":0.3178647807111346,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}