{"id":"W1981046216","doi":"10.1182/blood.v97.8.2230","title":"A common epitope is shared by activated signal transducer and activator of transcription-5 (STAT5) and the phosphorylated erythropoietin receptor: implications for the docking model of STAT activation","year":2001,"lang":"en","type":"article","venue":"Blood","topic":"Cytokine Signaling Pathways and Interactions","field":"Medicine","cited_by":48,"is_retracted":false,"has_abstract":true,"ca_institutions":"Toronto General Hospital; University of Toronto; Ontario Institute for Cancer Research","funders":"National Institute of Diabetes and Digestive and Kidney Diseases; National Cancer Institute","keywords":"SH2 domain; Tyrosine phosphorylation; STAT protein; STAT5; Erythropoietin receptor; Tyrosine; Protein tyrosine phosphatase; Phosphorylation; Molecular biology; Biology; Receptor tyrosine kinase; Cell biology; Cancer research; Signal transduction; STAT3; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001958034,0.0001469197,0.0003055387,0.00005390147,0.0002185777,0.00002221569,0.00007821742,0.00007761567,0.0001352126],"category_scores_gemma":[0.00004295219,0.00009235161,0.0001120043,0.0001955498,0.0002026127,0.0001492711,0.00001112498,0.0001805334,2.001211e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000018798,"about_ca_system_score_gemma":0.00005873799,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000276679,"about_ca_topic_score_gemma":0.00001001746,"domain_scores_codex":[0.9990876,0.00004274398,0.0003758088,0.0002083321,0.0001331067,0.000152364],"domain_scores_gemma":[0.9988757,0.0004489263,0.0002054859,0.0002208146,0.000194402,0.00005466934],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001355449,0.0003794704,0.0005061718,0.00005822317,0.0002884277,4.4976e-8,0.003300112,0.00005831632,0.9885906,0.0002442336,0.001048899,0.004170058],"study_design_scores_gemma":[0.006784276,0.0002645673,0.001304762,0.0001605295,0.0004819937,0.00001320124,0.0007307634,0.0063873,0.9814428,0.0004133679,0.001905695,0.0001107551],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9826093,0.0005409837,0.006881383,0.008273702,0.00002411554,0.001032167,0.0005299592,0.00002565416,0.00008271047],"genre_scores_gemma":[0.998314,0.0008160692,0.000343511,0.0002039859,0.00002978184,0.0001208628,0.00009631345,0.0000252768,0.00005025879],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01570462,"threshold_uncertainty_score":0.3765989,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02860911372819697,"score_gpt":0.2778431712020344,"score_spread":0.2492340574738374,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}