{"id":"W1981046216","doi":"10.1182/blood.v97.8.2230","title":"A common epitope is shared by activated signal transducer and activator of transcription-5 (STAT5) and the phosphorylated erythropoietin receptor: implications for the docking model of STAT activation","year":2001,"lang":"en","type":"article","venue":"Blood","topic":"Cytokine Signaling Pathways and Interactions","field":"Medicine","cited_by":48,"is_retracted":false,"has_abstract":true,"ca_institutions":"Toronto General Hospital; University of Toronto; Ontario Institute for Cancer Research","funders":"National Institute of Diabetes and Digestive and Kidney Diseases; National Cancer Institute","keywords":"SH2 domain; Tyrosine phosphorylation; STAT protein; STAT5; Erythropoietin receptor; Tyrosine; Protein tyrosine phosphatase; Phosphorylation; Molecular biology; Biology; Receptor tyrosine kinase; Cell biology; Cancer research; Signal transduction; STAT3; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001199788,0.0002844447,0.0002558898,0.0001705451,0.0001529151,0.0002822633,0.0003808725,0.0005241158,0.002276069],"category_scores_gemma":[0.0001290886,0.0001457234,0.0005106321,0.0001607591,0.0002045873,0.0004603331,0.0003207429,0.0003801345,0.000713981],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002556769,"about_ca_system_score_gemma":0.0001661089,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000278751,"about_ca_topic_score_gemma":0.0002460594,"domain_scores_codex":[0.9998599,0.00002128168,0.000009374803,0.00003742636,0.00003594497,0.00003590564],"domain_scores_gemma":[0.9999108,0.00001521202,0.00002864926,0.000008228284,0.0000100542,0.00002706336],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002291851,0.00002777103,0.000972927,0.00006626226,0.00001733026,0.0005888373,0.00004472008,0.0002285495,0.9922569,0.0022195,0.0001108072,0.003237084],"study_design_scores_gemma":[0.0002084701,0.001361406,0.09431265,0.00009855811,0.0001385413,0.01256174,0.0003384217,0.01920976,0.8458689,0.004060782,0.02178719,0.00005355355],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9823303,0.002276659,0.01154323,0.0002623982,0.00007592003,0.0000246468,0.000119927,0.00005131453,0.003315592],"genre_scores_gemma":[0.9934628,0.0006060306,0.003885378,0.0001970054,0.00002736985,0.0000132766,0.0003202022,0.00000876082,0.001479242],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002276069,"threshold_uncertainty_score":0.007614195,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02860911372819697,"score_gpt":0.2778431712020344,"score_spread":0.2492340574738374,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}