{"id":"W1981066202","doi":"10.1371/journal.ppat.1002784","title":"The Rhoptry Proteins ROP18 and ROP5 Mediate <em>Toxoplasma gondii</em> Evasion of the Murine, But Not the Human, Interferon-Gamma Response","year":2016,"lang":"en","type":"article","venue":"Figshare","topic":"Toxoplasma gondii Research Studies","field":"Immunology and Microbiology","cited_by":237,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"National Institute of General Medical Sciences; National Institute of Allergy and Infectious Diseases; Canadian Institutes of Health Research","keywords":"Rhoptry; Biology; Virulence; Toxoplasma gondii; Effector; Interferon; Intracellular parasite; Immune system; Microbiology; Cell biology; Gene; Virology; Genetics; Antibody; Immunology; Apicomplexa","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["sts","insufficient_payload"],"consensus_categories":["insufficient_payload"],"category_scores_codex":[0.0008997864,0.0004178127,0.0004219688,0.0001202176,0.001357766,0.00007533966,0.001391666,0.0003728156,0.008876609],"category_scores_gemma":[0.007650808,0.0001722708,0.000216316,0.0002393681,0.0005409375,0.0001563252,0.001984805,0.0007090631,0.001649581],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001080861,"about_ca_system_score_gemma":0.0001940903,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0000132442,"about_ca_topic_score_gemma":0.0006491637,"domain_scores_codex":[0.9964025,0.001408907,0.0005505805,0.0005529542,0.0002571477,0.0008279277],"domain_scores_gemma":[0.9950995,0.002880387,0.0003976228,0.001209174,0.0003515061,0.00006175178],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001940252,0.0000851872,0.0001779774,0.0001206742,0.000326281,0.00001435364,0.001351746,7.998599e-7,0.8256232,0.0001360132,0.1610692,0.00915428],"study_design_scores_gemma":[0.002034146,0.0006590222,0.05976846,0.00157579,0.00004135952,0.00009239067,0.0004900334,0.000002681363,0.5598509,0.0001193176,0.3750187,0.0003471531],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9488528,0.004070919,0.000001112168,0.00466855,0.0003560749,0.001677922,0.03983183,0.0001053418,0.0004354034],"genre_scores_gemma":[0.9776564,0.0002228498,0.000008460285,0.0001335859,0.0001062111,0.0007949618,0.0007820035,0.00005390118,0.02024168],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2657723,"threshold_uncertainty_score":0.9999423,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0259829381592486,"score_gpt":0.2593887169848739,"score_spread":0.2334057788256253,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}