{"id":"W1981136207","doi":"10.1016/j.clinbiochem.2007.07.016","title":"Proinflammatory and proapoptotic effects of methylglyoxal on neutrophils from patients with type 2 diabetes mellitus","year":2007,"lang":"en","type":"article","venue":"Clinical Biochemistry","topic":"Advanced Glycation End Products research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":142,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Saskatchewan","funders":"Canadian Institutes of Health Research; Heart and Stroke Foundation of Canada","keywords":"Proinflammatory cytokine; Methylglyoxal; Internal medicine; Endocrinology; Type 2 Diabetes Mellitus; Glycated hemoglobin; Diabetes mellitus; Apoptosis; Cytokine; Inflammation; Basal (medicine); Medicine; Creatinine; Chemistry; Type 2 diabetes; Biochemistry; Enzyme","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000326045,0.000157049,0.0002143946,0.00002139051,0.00003355581,0.000007464063,0.0001577651,0.0002067034,0.000006671511],"category_scores_gemma":[0.00139619,0.0001262485,0.00004603782,0.0000982522,0.0003114835,0.000003670044,0.0000957794,0.0002041064,0.00000537593],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001027689,"about_ca_system_score_gemma":0.00007437349,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":9.371324e-7,"about_ca_topic_score_gemma":3.721171e-7,"domain_scores_codex":[0.9986224,0.00005531468,0.0003443142,0.0005273944,0.0002049726,0.0002456383],"domain_scores_gemma":[0.9987012,0.0002592514,0.0001505909,0.0005016379,0.000222139,0.0001651595],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0008532503,0.0003709709,0.08361124,0.0002210131,0.0001246342,0.000003158643,0.000009364681,0.000002770419,0.8983969,0.000009067946,0.000128617,0.01626902],"study_design_scores_gemma":[0.0009807411,0.0008842077,0.07893235,0.00005367872,0.00002130021,1.951134e-7,0.000005526185,0.00000180379,0.9180967,0.00006574181,0.0008116055,0.0001461716],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9980605,0.001274579,0.00008061594,0.00003743396,0.0001015439,0.0002864524,0.00001204264,0.00001055155,0.0001363274],"genre_scores_gemma":[0.9976776,0.0001802108,0.001467577,0.00008654463,0.0002696147,0.000007369821,0.0001733388,0.00002266129,0.0001150889],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01969979,"threshold_uncertainty_score":0.5148266,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0101449506631026,"score_gpt":0.308133581261032,"score_spread":0.2979886305979293,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}