{"id":"W1981214889","doi":"10.3390/antib2020193","title":"In Vivo Applications of Single Chain Fv (Variable Domain) (scFv) Fragments","year":2013,"lang":"en","type":"article","venue":"Antibodies","topic":"Monoclonal and Polyclonal Antibodies Research","field":"Medicine","cited_by":131,"is_retracted":false,"has_abstract":true,"ca_institutions":"Toronto Western Hospital; University of Toronto","funders":"","keywords":"In vivo; Single-chain variable fragment; Computational biology; Monoclonal antibody; Antibody; Function (biology); Biology; Chemistry; Cell biology; Immunology; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003327032,0.0004810817,0.0002937479,0.0003130939,0.0001066174,0.0003067781,0.0002206137,0.0004465281,0.001838842],"category_scores_gemma":[0.0001855521,0.0001209256,0.0002565132,0.0001533549,0.0001323091,0.0001998491,0.0001252172,0.0005495235,0.0004171453],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002372097,"about_ca_system_score_gemma":0.0001417875,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004922262,"about_ca_topic_score_gemma":0.0004954049,"domain_scores_codex":[0.9998486,0.0000448008,0.000008843559,0.00002922049,0.00004382485,0.00002461563],"domain_scores_gemma":[0.9999233,0.00002470592,0.00001829532,0.000009285322,0.00001320636,0.00001112956],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002486664,0.0001323115,0.000238756,0.0002632128,0.0000163609,0.000142957,0.00002856536,0.000245274,0.9680494,0.0003739651,0.0005717992,0.02968872],"study_design_scores_gemma":[0.00004467756,0.00152719,0.001974972,0.00004563546,0.00006648626,0.001283612,0.00002779066,0.001033701,0.9704485,0.0001771182,0.02336403,0.00000628246],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.7293058,0.1099627,0.1193444,0.0010691,0.0005792175,0.0004782748,0.001123974,0.001068216,0.03706824],"genre_scores_gemma":[0.9205124,0.03766021,0.02845163,0.000370709,0.0001503404,0.000172915,0.0008617096,0.00009590132,0.01172415],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001838842,"threshold_uncertainty_score":0.006151497,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01685820071016198,"score_gpt":0.2930924598618728,"score_spread":0.2762342591517108,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}