{"id":"W1981242936","doi":"10.1021/jo0108717","title":"Efficient Synthesis of IPL576,092:  A Novel Anti-Asthma Agent","year":2002,"lang":"en","type":"article","venue":"The Journal of Organic Chemistry","topic":"Analytical Chemistry and Chromatography","field":"Chemistry","cited_by":46,"is_retracted":false,"has_abstract":true,"ca_institutions":"Inflazyme (Canada)","funders":"","keywords":"Chemistry; Stereoselectivity; Enone; Hydroboration; Combinatorial chemistry; Total synthesis; Chemical synthesis; Stereochemistry; Organic chemistry; Catalysis; Biochemistry; In vitro","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002045143,0.0006230504,0.0005626632,0.0002979428,0.0002052095,0.0003468817,0.0006024357,0.0004264318,0.003843044],"category_scores_gemma":[0.0001218961,0.0002443509,0.0003201694,0.0002593788,0.0001782266,0.0004073406,0.0004603443,0.0007161645,0.002328948],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002409834,"about_ca_system_score_gemma":0.0003772142,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002532814,"about_ca_topic_score_gemma":0.0005237285,"domain_scores_codex":[0.9998757,0.00001851165,0.00001252122,0.00002587189,0.00003358813,0.0000338016],"domain_scores_gemma":[0.9999557,0.000003220851,0.000009100101,0.000006955001,0.000008114208,0.00001695879],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002724934,0.0001602976,0.0001110757,0.0003000499,0.00002840045,0.0006722521,0.0000408061,0.0006793203,0.9735643,0.0008729195,0.0006172074,0.02268074],"study_design_scores_gemma":[0.0001947874,0.0007895901,0.0007631662,0.00001508542,0.00004704401,0.001135387,0.00001946887,0.0007118894,0.9719705,0.0001832752,0.02414345,0.00002637964],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.8382066,0.01465106,0.08758886,0.0008898397,0.0004747495,0.0008797956,0.005109522,0.00133363,0.05086591],"genre_scores_gemma":[0.938109,0.006318885,0.03614577,0.000329931,0.00008894821,0.0002718725,0.002553847,0.0001389456,0.01604284],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003843044,"threshold_uncertainty_score":0.01285625,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01094640883271818,"score_gpt":0.200637530373583,"score_spread":0.1896911215408648,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}