{"id":"W1981249718","doi":"10.1074/jbc.275.9.6600","title":"Characterization of a Repressor Element and a Juxtaposed Tissue-restricted Activator Element Located on the Distal neu Gene Promoter","year":2000,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"HER2/EGFR in Cancer Research","field":"Medicine","cited_by":8,"is_retracted":false,"has_abstract":true,"ca_institutions":"Princess Margaret Cancer Centre; Occupational Cancer Research Centre; Cancer Care Ontario; Ontario Institute for Cancer Research","funders":"","keywords":"Repressor; Molecular biology; Biology; Promoter; Gene; Transcription (linguistics); DNA; Reporter gene; Base pair; Response element; Activator (genetics); Transcription factor; Genetics; Gene expression","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000209364,0.0002782198,0.0002851985,0.0002111239,0.0001178822,0.0002598579,0.000419345,0.0002567456,0.001381205],"category_scores_gemma":[0.0003895359,0.0001873433,0.0003880642,0.0001290769,0.0002191376,0.0001650768,0.000218819,0.0007443722,0.001172814],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002397431,"about_ca_system_score_gemma":0.0003708882,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008326691,"about_ca_topic_score_gemma":0.0008156578,"domain_scores_codex":[0.9998567,0.00001811245,0.00001035336,0.00004092312,0.00004705243,0.00002679489],"domain_scores_gemma":[0.99971,0.00009201005,0.00005581123,0.00003041827,0.00003972394,0.00007203909],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00005496369,0.0000140744,0.0001335039,0.00002282765,0.000001574773,0.00003635426,0.000009708545,0.00004317212,0.9988127,0.00008630312,0.000006839119,0.0007780452],"study_design_scores_gemma":[0.00002444683,0.0001670477,0.005304484,0.00001879613,0.00002005533,0.0007452142,0.0000348586,0.002501664,0.9864882,0.0000809847,0.004604914,0.000009270816],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9536389,0.001856211,0.04119525,0.0001721167,0.00004160913,0.0000888494,0.0008723225,0.0001489691,0.001985813],"genre_scores_gemma":[0.9587226,0.0008212471,0.03052002,0.0001042485,0.00002320679,0.00006364421,0.004316685,0.00009106845,0.005337318],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001381205,"threshold_uncertainty_score":0.004620612,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04332741759104532,"score_gpt":0.3205122740676372,"score_spread":0.2771848564765919,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}