{"id":"W1981255819","doi":"10.1038/cr.2008.176","title":"NUMB mediates the interaction between Wnt and Notch to modulate primitive erythropoietic specification from the hemangioblast","year":2008,"lang":"en","type":"article","venue":"Cell Research","topic":"Epigenetics and DNA Methylation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":11,"is_retracted":false,"has_abstract":false,"ca_institutions":"University Health Network","funders":"","keywords":"Hemangioblast; Biology; NUMB; Wnt signaling pathway; Notch signaling pathway; Cell biology; Genetics; Stem cell; Haematopoiesis; Signal transduction","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005469438,0.00008672649,0.00007394006,0.00003294101,0.0003542677,0.00004689285,0.0002050672,0.00008080668,0.00002328041],"category_scores_gemma":[0.0001570701,0.00005553587,0.00003448616,0.0001425961,0.0001978274,0.000004287813,0.0001835898,0.0001946831,0.00006120311],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002237787,"about_ca_system_score_gemma":0.00004095248,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001792648,"about_ca_topic_score_gemma":0.00005207392,"domain_scores_codex":[0.9988362,0.0002287694,0.0001443866,0.0002977137,0.0002808915,0.0002120174],"domain_scores_gemma":[0.9990667,0.0002831288,0.00003816238,0.000341834,0.000192649,0.00007750819],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00005266953,0.00003539499,0.01147542,0.000004918929,0.00002802616,0.000001296972,0.001573928,0.00008338402,0.9768164,0.00002365009,0.001622002,0.008282985],"study_design_scores_gemma":[0.0001492387,0.0001536804,0.1373676,0.000007784114,0.000007459949,7.700652e-7,0.0006171654,0.0001125278,0.8417695,0.0003490259,0.01938116,0.00008405548],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9940674,0.001216962,0.001168071,0.001937911,0.0000685667,0.0003404197,0.00001365492,0.000004483891,0.001182529],"genre_scores_gemma":[0.9966634,0.001940942,0.0001576779,0.00004472962,0.0005635463,0.00002304527,0.0001009123,0.00001575633,0.0004900231],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1350468,"threshold_uncertainty_score":0.2724777,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.08654761688768411,"score_gpt":0.3513876772067525,"score_spread":0.2648400603190684,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}