{"id":"W1981255819","doi":"10.1038/cr.2008.176","title":"NUMB mediates the interaction between Wnt and Notch to modulate primitive erythropoietic specification from the hemangioblast","year":2008,"lang":"en","type":"article","venue":"Cell Research","topic":"Epigenetics and DNA Methylation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":11,"is_retracted":false,"has_abstract":false,"ca_institutions":"University Health Network","funders":"","keywords":"Hemangioblast; Biology; NUMB; Wnt signaling pathway; Notch signaling pathway; Cell biology; Genetics; Stem cell; Haematopoiesis; Signal transduction","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003329612,0.0002221538,0.0002798015,0.0001940175,0.0004525589,0.0008262277,0.0004308488,0.0003102465,0.00186257],"category_scores_gemma":[0.0004885254,0.0003747583,0.0001687538,0.0001096041,0.0004938664,0.0007142506,0.0007732744,0.0007207783,0.0007125319],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0009884391,"about_ca_system_score_gemma":0.0004709588,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001006456,"about_ca_topic_score_gemma":0.002693605,"domain_scores_codex":[0.9997498,0.00004950262,0.00001731943,0.00004570609,0.00007997417,0.0000577355],"domain_scores_gemma":[0.9997615,0.00004391323,0.00005422524,0.00002899698,0.00002275939,0.00008853509],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001741431,0.000006757812,0.0004973226,0.00002427037,0.000005244391,0.00006341265,0.00003322621,0.0001174371,0.9958911,0.001236891,0.00005291942,0.001897227],"study_design_scores_gemma":[0.00003549072,0.00005797788,0.01060119,0.00001423155,0.00001401129,0.0001867532,0.00009879813,0.002812848,0.9812667,0.0005092183,0.00439622,0.00000651594],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9817618,0.003950133,0.007316635,0.0003476499,0.00005809782,0.00001663788,0.0002108688,0.00008170696,0.0062566],"genre_scores_gemma":[0.9904784,0.0008119249,0.002351407,0.00005956899,0.00001052188,0.00001590626,0.0001926945,0.00003702177,0.006042564],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00186257,"threshold_uncertainty_score":0.007171631,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.08654761688768411,"score_gpt":0.3513876772067525,"score_spread":0.2648400603190684,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}