{"id":"W1981288226","doi":"10.1080/02656730310001637334","title":"Role of nuclear protein denaturation and aggregation in thermal radiosensitization","year":2004,"lang":"en","type":"review","venue":"International Journal of Hyperthermia","topic":"Heat shock proteins research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":91,"is_retracted":false,"has_abstract":true,"ca_institutions":"Princess Margaret Cancer Centre; Ontario Institute for Cancer Research; University of Toronto","funders":"","keywords":"Denaturation (fissile materials); Protein aggregation; Chemistry; Radiochemistry; Biophysics; Biochemistry; Biology; Nuclear chemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003073314,0.0001455538,0.0003729749,0.0002833168,0.00001557336,0.00002873778,0.0002704822,0.0002441528,0.00001348407],"category_scores_gemma":[0.0001960992,0.000120225,0.0001452439,0.00008427011,0.0000498132,0.00001744421,0.00006957151,0.0002482846,0.00000232112],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001067854,"about_ca_system_score_gemma":0.0003822602,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0000229183,"about_ca_topic_score_gemma":0.00001174563,"domain_scores_codex":[0.9986733,0.0001417082,0.000575367,0.0001486123,0.0003604363,0.0001006074],"domain_scores_gemma":[0.9990067,0.00001481908,0.0004573187,0.0001107057,0.0003670092,0.00004340392],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00008917697,0.00005843702,0.00001466883,0.0004362186,0.0001979452,0.00003069687,0.00005855754,0.00004601949,0.1252098,0.0000780997,0.000003820663,0.8737766],"study_design_scores_gemma":[0.003816778,0.001330525,0.0005709659,0.03821765,0.0002514357,0.003258341,0.0001679817,0.0002202528,0.06641678,0.0005871243,0.8842112,0.0009509313],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.08191106,0.9173957,0.00002749181,0.00004841872,0.00007949006,0.0003664133,0.00001079943,0.000001844426,0.0001588004],"genre_scores_gemma":[0.1297413,0.8691919,0.0005875552,0.00001326999,0.0003327155,0.000007528502,0.00005396989,0.00004002593,0.00003164924],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.8842074,"threshold_uncertainty_score":0.4902635,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01182886352223382,"score_gpt":0.3008447624865274,"score_spread":0.2890158989642936,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}