{"id":"W1981305922","doi":"10.1007/s10930-006-9050-3","title":"Single Molecule Assays of β-Galactosidase from Two Wild-type Strains of E. coli: Effects of Protease Inhibitors on Microheterogeneity and Different Relative Activities with Differing Substrates","year":2007,"lang":"en","type":"article","venue":"The Protein Journal","topic":"Enzyme Catalysis and Immobilization","field":"Biochemistry, Genetics and Molecular Biology","cited_by":16,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Winnipeg; University of Manitoba","funders":"","keywords":"Protease; Enzyme; Biochemistry; Capillary electrophoresis; Chemistry; Bioorganic chemistry; Bacteria; Enzyme assay; Biology; Molecular biology; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001909129,0.0001332659,0.0001997425,0.00004296136,0.0000568628,0.00001212021,0.00008509617,0.00005793471,0.000002286357],"category_scores_gemma":[0.00008153835,0.00008284129,0.00006222587,0.00006676385,0.000172427,0.000009942286,0.00003713162,0.0001279472,3.941052e-8],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001362381,"about_ca_system_score_gemma":0.0000310139,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001995106,"about_ca_topic_score_gemma":0.00002761072,"domain_scores_codex":[0.9992217,0.0001151939,0.0002562467,0.0001318216,0.0001501817,0.0001248197],"domain_scores_gemma":[0.9992628,0.00004098065,0.0003836226,0.0001614253,0.00009865871,0.00005251745],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0004843509,0.0001760306,0.004893423,0.00005801623,0.0001435876,0.00000230848,0.0002550702,0.00004023383,0.9935208,0.00001736509,0.00000124856,0.0004075673],"study_design_scores_gemma":[0.0007341846,0.001576927,0.01729949,0.0002700561,0.00005726445,0.000006257588,0.0001372443,0.00001230595,0.9797494,0.00007026289,0.000001696131,0.00008494793],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9959897,0.0005173596,0.003024466,0.00001270616,0.00002075351,0.0004000117,0.00001308895,0.000001893141,0.00001997912],"genre_scores_gemma":[0.9996833,0.00002220995,0.000196037,0.000005324122,0.00004968541,0.000005356337,0.00001367015,0.00001374103,0.00001066547],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01377144,"threshold_uncertainty_score":0.337817,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.00809780254364606,"score_gpt":0.2240606577896447,"score_spread":0.2159628552459986,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}