{"id":"W1981372060","doi":"10.1093/cvr/cvq328","title":"Cathepsin-L contributes to cardiac repair and remodelling post-infarction","year":2010,"lang":"en","type":"article","venue":"Cardiovascular Research","topic":"Protease and Inhibitor Mechanisms","field":"Biochemistry, Genetics and Molecular Biology","cited_by":67,"is_retracted":false,"has_abstract":true,"ca_institutions":"McMaster University; Toronto General Hospital; Canadian Institutes of Health Research; Heart and Stroke Foundation; University Health Network","funders":"Institute of Circulatory and Respiratory Health; Canadian Institutes of Health Research; University of Toronto; Heart and Stroke Foundation of Canada","keywords":"Cathepsin L; Myofibroblast; Myocardial infarction; Cathepsin; Arteriogenesis; Internal medicine; Angiogenesis; Medicine; Biology; Endocrinology; Cell biology; Fibrosis","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.003061255,0.0001359618,0.0002309506,0.0001414381,0.0002683487,0.00006629469,0.0001721603,0.0002339734,0.000005802361],"category_scores_gemma":[0.0006006769,0.0001319525,0.0004445031,0.0002048359,0.0001095788,0.00000705432,0.000288378,0.0004000418,0.00003846104],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002018928,"about_ca_system_score_gemma":0.000107315,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001655177,"about_ca_topic_score_gemma":0.00001386094,"domain_scores_codex":[0.9981341,0.0002504274,0.0001479343,0.0005774984,0.0004393492,0.0004506993],"domain_scores_gemma":[0.9981911,0.00002167013,0.00001311346,0.000939036,0.0006233637,0.0002116813],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00006133042,0.00001504607,0.0001699027,0.00001898631,0.0004002437,0.000006121453,0.00002915773,0.00002833181,0.9906244,0.0005876448,0.001675831,0.006383002],"study_design_scores_gemma":[0.0002784863,0.00017695,0.0003420472,0.00001449446,0.0000396856,0.00001834944,0.00007741954,0.00008495232,0.6903702,0.0003501737,0.3080832,0.0001640212],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9853439,0.008574668,0.003336313,0.0002866843,0.0004604004,0.0007684588,0.00002052374,0.00004349872,0.001165511],"genre_scores_gemma":[0.9967558,0.0004813092,0.001310525,0.0001317015,0.0007212993,0.0001162711,0.00005220486,0.00003647728,0.0003944285],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.3064074,"threshold_uncertainty_score":0.5380869,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02076619386832304,"score_gpt":0.297888315220704,"score_spread":0.277122121352381,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}