{"id":"W1981374189","doi":"10.1172/jci35197","title":"Islet transplantation in patients with autoimmune diabetes induces homeostatic cytokines that expand autoreactive memory T cells","year":2008,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Diabetes and associated disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":192,"is_retracted":false,"has_abstract":true,"ca_institutions":"Juvenile Diabetes Research Foundation","funders":"Zentrum für Regenerative Therapien Dresden; Ministero della Salute; Technische Universität Dresden","keywords":"Immunology; Autoimmunity; Transplantation; Immunosuppression; T cell; Autoimmune disease; Immune system; Medicine; Islet; Biology; Diabetes mellitus; Endocrinology; Internal medicine; Antibody","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002660953,0.0003003485,0.0003329936,0.0003087964,0.0001746237,0.0002930435,0.00008596924,0.0002935642,0.0009868015],"category_scores_gemma":[0.0004338949,0.00008052436,0.0001784274,0.0002691875,0.000179028,0.0001887292,0.0001357768,0.0004574707,0.0002369434],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001043768,"about_ca_system_score_gemma":0.0001237914,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00008903651,"about_ca_topic_score_gemma":0.00009476639,"domain_scores_codex":[0.9998869,0.00004058583,0.00001333394,0.00001737466,0.00002004462,0.00002180951],"domain_scores_gemma":[0.9998073,0.00005546983,0.00005508484,0.00001968557,0.00001447072,0.00004806638],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.002945474,0.0006726852,0.3986798,0.0002627757,0.0001284875,0.0129678,0.0003376279,0.0002477341,0.4468915,0.000329286,0.001038036,0.1354987],"study_design_scores_gemma":[0.0003550688,0.007270257,0.8024155,0.00006525619,0.0003333995,0.0686784,0.0002899549,0.0009596504,0.1096778,0.0006008547,0.009332675,0.00002103536],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9931177,0.004296083,0.0007026178,0.0001923129,0.0000303481,0.00001682304,0.00003450251,0.00007936011,0.001530339],"genre_scores_gemma":[0.9982607,0.0008767991,0.0003648471,0.0001190174,0.00006985417,0.000009285481,0.00007984674,0.000006436933,0.0002132986],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0009868015,"threshold_uncertainty_score":0.003301203,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02148051750440207,"score_gpt":0.2672143550368892,"score_spread":0.2457338375324871,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}