{"id":"W1981404696","doi":"10.1038/ncb916","title":"Fas engagement induces neurite growth through ERK activation and p35 upregulation","year":2003,"lang":"en","type":"article","venue":"Nature Cell Biology","topic":"Cell death mechanisms and regulation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":305,"is_retracted":false,"has_abstract":false,"ca_institutions":"McGill University","funders":"National Institutes of Health","keywords":"Neurite; Cell biology; MAPK/ERK pathway; Downregulation and upregulation; Fas receptor; Nerve growth factor; Apoptosis; Mediator; In vivo; Receptor; Signal transduction; Chemistry; Biology; In vitro; Programmed cell death; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001791307,0.00015126,0.0001120836,0.00003923826,0.000123964,0.00001629899,0.00006639777,0.0006543483,0.00002555221],"category_scores_gemma":[0.00006545732,0.0001293616,0.00004187355,0.00008157393,0.00004843199,0.000008257021,0.00004416374,0.0002242202,0.000002668497],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001074051,"about_ca_system_score_gemma":0.00002346207,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000007283815,"about_ca_topic_score_gemma":0.000003723303,"domain_scores_codex":[0.9990801,0.0001547429,0.0001450235,0.0003787902,0.00006222446,0.0001790933],"domain_scores_gemma":[0.999607,0.00001964163,0.00009258544,0.0001714583,0.00007288727,0.00003637438],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00002336997,0.00003129173,0.0005165478,0.00001519723,0.00001520733,3.548885e-7,0.00005194398,0.00001674239,0.9844935,0.01247387,0.0002861817,0.002075809],"study_design_scores_gemma":[0.0004429421,0.000187572,0.003203541,0.000004782092,0.00001429463,0.000004615732,0.00004032986,0.00002593705,0.8977863,0.004246194,0.09387843,0.000165094],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9865493,0.001967054,0.004832643,0.0001842119,0.0004109093,0.0002483653,0.000004976895,0.0000176751,0.005784839],"genre_scores_gemma":[0.9960105,0.000636015,0.00195245,0.0004465052,0.0001810673,0.00001209381,0.0002993432,0.00001501303,0.0004469519],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.09359225,"threshold_uncertainty_score":0.5275213,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008596810101124215,"score_gpt":0.2457061161443539,"score_spread":0.2371093060432297,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}