{"id":"W1981447099","doi":"10.1126/science.1180512","title":"<i>O</i> -Mannosyl Phosphorylation of Alpha-Dystroglycan Is Required for Laminin Binding","year":2009,"lang":"en","type":"article","venue":"Science","topic":"Muscle Physiology and Disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":332,"is_retracted":false,"has_abstract":true,"ca_institutions":"Hospital for Sick Children","funders":"National Center for Research Resources; National Institute of Neurological Disorders and Stroke; National Institute of Allergy and Infectious Diseases; University of California, San Diego; National Institutes of Health; Howard Hughes Medical Institute; National Institute of Diabetes and Digestive and Kidney Diseases; U.S. Department of Defense","keywords":"Laminin; Dystroglycan; Congenital muscular dystrophy; Phosphorylation; Glycoprotein; Muscular dystrophy; Cell biology; Extracellular matrix; Biology; Chemistry; Biochemistry; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0000964362,0.0002754689,0.0001837975,0.0001024491,0.0002145282,0.0004276106,0.0002295559,0.0002132345,0.001170279],"category_scores_gemma":[0.0002646397,0.0001813161,0.0001843286,0.00008748731,0.0002247637,0.000201217,0.0003044998,0.0002970862,0.0006686765],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004240589,"about_ca_system_score_gemma":0.0003212491,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001380592,"about_ca_topic_score_gemma":0.001581195,"domain_scores_codex":[0.9998441,0.00003015395,0.00002046035,0.00002768703,0.00003245554,0.00004509607],"domain_scores_gemma":[0.999718,0.0000434938,0.00007692006,0.00002700694,0.00002165748,0.0001128777],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00009541692,0.00001574415,0.0005409744,0.00001511349,0.000002821995,0.0002340366,0.0000155439,0.00007013127,0.9981136,0.0001787418,0.00005656367,0.0006611737],"study_design_scores_gemma":[0.00002061964,0.0001101841,0.02450614,0.00001187599,0.00001316917,0.0010688,0.00009497472,0.001421,0.9699898,0.0002219549,0.002532671,0.00000875673],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9974106,0.0003616805,0.0007328542,0.00009375945,0.00001174295,0.000005033265,0.0001438234,0.00006615973,0.00117443],"genre_scores_gemma":[0.9982588,0.0001043661,0.0006448448,0.00003115874,0.000003438798,0.000006864507,0.0002565211,0.00002050959,0.000673539],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001380592,"threshold_uncertainty_score":0.003914952,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01289105759554887,"score_gpt":0.2816771292075794,"score_spread":0.2687860716120305,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}