{"id":"W1981447099","doi":"10.1126/science.1180512","title":"<i>O</i> -Mannosyl Phosphorylation of Alpha-Dystroglycan Is Required for Laminin Binding","year":2009,"lang":"en","type":"article","venue":"Science","topic":"Muscle Physiology and Disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":332,"is_retracted":false,"has_abstract":true,"ca_institutions":"Hospital for Sick Children","funders":"National Center for Research Resources; National Institute of Neurological Disorders and Stroke; National Institute of Allergy and Infectious Diseases; University of California, San Diego; National Institutes of Health; Howard Hughes Medical Institute; National Institute of Diabetes and Digestive and Kidney Diseases; U.S. Department of Defense","keywords":"Laminin; Dystroglycan; Congenital muscular dystrophy; Phosphorylation; Glycoprotein; Muscular dystrophy; Cell biology; Extracellular matrix; Biology; Chemistry; Biochemistry; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002086226,0.00005877856,0.00006770028,0.00003526672,0.0001056816,0.000007277327,0.0001940281,0.00004634047,0.000006524785],"category_scores_gemma":[0.00008032241,0.00005626459,0.00003990496,0.0001561145,0.0002184075,0.000008041242,0.00002428143,0.00001968721,0.000002155678],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000004891155,"about_ca_system_score_gemma":0.00008329682,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000002072613,"about_ca_topic_score_gemma":0.000001524798,"domain_scores_codex":[0.999388,0.000006860604,0.0001063918,0.0002396292,0.00008345471,0.000175649],"domain_scores_gemma":[0.9996432,0.00000611749,0.00006830782,0.0001761303,0.00007031432,0.00003594868],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00006174405,0.00002126583,0.0003706404,0.000003473297,0.000002236402,5.119844e-8,0.00005126205,0.0000158944,0.9937338,0.000417813,0.0006608928,0.004660984],"study_design_scores_gemma":[0.0003065055,0.0005159326,0.007882968,0.000006094676,0.000004156107,6.899115e-7,0.00006367388,0.000180467,0.9865683,0.00108031,0.003307419,0.00008345881],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9970354,0.0001548048,0.001139171,0.0002099799,0.0000910376,0.0001153007,0.00001293727,0.000005478201,0.001235931],"genre_scores_gemma":[0.998525,0.00002095135,0.0008133674,0.0003901917,0.0000330475,0.000004931249,0.00001902268,0.000002699819,0.0001908246],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.007512327,"threshold_uncertainty_score":0.2294404,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01289105759554887,"score_gpt":0.2816771292075794,"score_spread":0.2687860716120305,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}