{"id":"W1981450549","doi":"10.1016/j.nbd.2008.05.008","title":"Amiloride is neuroprotective in an MPTP model of Parkinson's disease","year":2008,"lang":"en","type":"article","venue":"Neurobiology of Disease","topic":"Neuroscience and Neuropharmacology Research","field":"Neuroscience","cited_by":122,"is_retracted":false,"has_abstract":false,"ca_institutions":"Women's Health Research Institute","funders":"","keywords":"MPTP; Amiloride; Substantia nigra; Neuroprotection; Dopamine; Dopamine transporter; Tyrosine hydroxylase; Pharmacology; Dopaminergic; Parkinson's disease; Chemistry; Medicine; Endocrinology; Internal medicine; Neuroscience; Biology; Disease","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003081197,0.0004052611,0.000954824,0.0005476084,0.000532239,0.0005283399,0.0005820451,0.000820645,0.001858046],"category_scores_gemma":[0.0004532967,0.0002619619,0.0002765257,0.0003718068,0.000573779,0.0009109782,0.0002257512,0.001533722,0.0004174648],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003785708,"about_ca_system_score_gemma":0.0005495481,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001402225,"about_ca_topic_score_gemma":0.001949407,"domain_scores_codex":[0.9998077,0.00003319067,0.0000216093,0.00002575163,0.00003809577,0.00007371977],"domain_scores_gemma":[0.9997466,0.00005852055,0.00003817851,0.00002011224,0.00003489253,0.0001016558],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.006659673,0.0003130957,0.0002666301,0.000131606,0.00004855089,0.0004532937,0.00007004281,0.000117532,0.9875616,0.0004014552,0.0002678977,0.00370877],"study_design_scores_gemma":[0.0008085544,0.01036361,0.008495136,0.00003848494,0.0001621103,0.001088763,0.000174336,0.001751939,0.9747352,0.0005795531,0.001769201,0.00003314841],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9922109,0.00337923,0.0007323701,0.0004313659,0.0001125098,0.00002913502,0.0002364405,0.0001299055,0.002738218],"genre_scores_gemma":[0.9959188,0.001640014,0.0006679761,0.00007070503,0.00007288242,0.00002451813,0.0003317912,0.00001363756,0.001259647],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001858046,"threshold_uncertainty_score":0.006215811,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0913709593894303,"score_gpt":0.3330525435749357,"score_spread":0.2416815841855054,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}