{"id":"W1981452763","doi":"10.1016/j.mce.2010.12.007","title":"Mitochondrial protein import and the genesis of steroidogenic mitochondria","year":2010,"lang":"en","type":"review","venue":"Molecular and Cellular Endocrinology","topic":"Mitochondrial Function and Pathology","field":"Biochemistry, Genetics and Molecular Biology","cited_by":87,"is_retracted":false,"has_abstract":false,"ca_institutions":"McGill University Health Centre; McGill University","funders":"National Institute of Environmental Health Sciences; National Institute for Health and Care Research; Canadian Institutes of Health Research; Canada Research Chairs; Health Canada; National Institutes of Health","keywords":"Translocator protein; Steroidogenic acute regulatory protein; Mitochondrion; Cell biology; Inner mitochondrial membrane; Cholesterol side-chain cleavage enzyme; Biology; Mitochondrial membrane transport protein; ATP–ADP translocase; Steroid biosynthesis; Translocase of the outer membrane; Protein targeting; Mitochondrial carrier; Biochemistry; Bacterial outer membrane; Membrane protein; Steroid; Hormone; Membrane; Cytochrome P450; Metabolism; Gene; Messenger RNA","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006449401,0.0009994898,0.001363385,0.001659935,0.0003668077,0.00116062,0.001182391,0.00174575,0.00143776],"category_scores_gemma":[0.0005022893,0.0003724436,0.0002927333,0.001703327,0.001120668,0.00217765,0.0009945035,0.00213779,0.0017708],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001262789,"about_ca_system_score_gemma":0.0009360835,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009268841,"about_ca_topic_score_gemma":0.001575029,"domain_scores_codex":[0.9998631,0.0000178241,0.00002007116,0.00003205142,0.0000516554,0.00001531659],"domain_scores_gemma":[0.9997223,0.0001040044,0.00004282947,0.00001470822,0.00008196821,0.00003421075],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001848746,0.00007290371,0.0003581783,0.009236562,0.00007888991,0.001163239,0.00008486897,0.0006042417,0.01248813,0.01593358,0.0345909,0.9252036],"study_design_scores_gemma":[0.00002748985,0.00004841908,0.0009502599,0.001112608,0.00006463088,0.003202955,0.00008710915,0.0001599648,0.00318655,0.008900288,0.9822307,0.00002893395],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0002091914,0.997569,0.0004750528,0.000485253,0.0003766558,0.000003274519,0.00001557334,0.000009611268,0.0008563747],"genre_scores_gemma":[0.001166787,0.9970742,0.0003403159,0.0002058842,0.0004009642,0.000005689237,0.00003059188,0.000001731783,0.0007736869],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.00174575,"threshold_uncertainty_score":0.009162188,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01274709053485006,"score_gpt":0.2517147134221834,"score_spread":0.2389676228873334,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}