{"id":"W1981464777","doi":"10.1002/1521-4141(200011)30:11<3079::aid-immu3079>3.0.co;2-7","title":"Generation and characterization of malaria-specific human CD8+ lymphocyte clones: effect of natural polymorphism on T cell recognition and endogenous cognate antigen presentationby liver cells","year":2000,"lang":"en","type":"article","venue":"European Journal of Immunology","topic":"Malaria Research and Control","field":"Medicine","cited_by":50,"is_retracted":false,"has_abstract":true,"ca_institutions":"Montreal Clinical Research Institute","funders":"Departamento Administrativo de Ciencia, Tecnología e Innovación (COLCIENCIAS)","keywords":"Biology; CTL*; ELISPOT; Antigen; Virology; Cytotoxic T cell; CD8; Epitope; Major histocompatibility complex; T cell; Immunology; Human leukocyte antigen; Molecular biology; Immune system; Genetics; In vitro","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001822667,0.0002763518,0.0002126768,0.0001293137,0.0001095643,0.000224201,0.0001654902,0.0002142635,0.001250911],"category_scores_gemma":[0.0002711037,0.0001214757,0.0001203805,0.0001405355,0.0001171447,0.00009695107,0.000163258,0.0004309271,0.0004851903],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001364149,"about_ca_system_score_gemma":0.0001075541,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002237826,"about_ca_topic_score_gemma":0.0002805695,"domain_scores_codex":[0.999844,0.00004136866,0.00001570291,0.00003582687,0.00002983353,0.000033297],"domain_scores_gemma":[0.9998863,0.00003803281,0.0000179673,0.00002073169,0.00001612911,0.00002091299],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001704547,0.000110581,0.0007765645,0.00003091067,0.000004970104,0.00006566344,0.00003305183,0.00008571954,0.996048,0.00003641493,0.00003603932,0.002601583],"study_design_scores_gemma":[0.0001994608,0.002871448,0.01493796,0.00001408415,0.00005343835,0.002951449,0.00007406717,0.001790328,0.971633,0.00008038873,0.005384415,0.00001002498],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9960976,0.0004690784,0.002584497,0.00003158867,0.000007752536,0.0001054389,0.0002054165,0.00001877205,0.0004799175],"genre_scores_gemma":[0.9933746,0.0004171893,0.003614773,0.00004265472,0.00001760746,0.0001432825,0.001147671,0.00001574654,0.001226305],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001250911,"threshold_uncertainty_score":0.004184783,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02897446631828256,"score_gpt":0.2315168796832408,"score_spread":0.2025424133649582,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}