{"id":"W1981464777","doi":"10.1002/1521-4141(200011)30:11<3079::aid-immu3079>3.0.co;2-7","title":"Generation and characterization of malaria-specific human CD8+ lymphocyte clones: effect of natural polymorphism on T cell recognition and endogenous cognate antigen presentationby liver cells","year":2000,"lang":"en","type":"article","venue":"European Journal of Immunology","topic":"Malaria Research and Control","field":"Medicine","cited_by":50,"is_retracted":false,"has_abstract":true,"ca_institutions":"Montreal Clinical Research Institute","funders":"Departamento Administrativo de Ciencia, Tecnología e Innovación (COLCIENCIAS)","keywords":"Biology; CTL*; ELISPOT; Antigen; Virology; Cytotoxic T cell; CD8; Epitope; Major histocompatibility complex; T cell; Immunology; Human leukocyte antigen; Molecular biology; Immune system; Genetics; In vitro","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005455791,0.0001220965,0.0003310074,0.0002248925,0.00006723033,0.00001687675,0.00007073775,0.00004353644,0.0002572312],"category_scores_gemma":[0.0000250062,0.00009801285,0.00006359031,0.0000766481,0.0001270918,0.0001144146,0.00001835531,0.0002043508,0.00001628948],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002384395,"about_ca_system_score_gemma":0.00003134943,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001205455,"about_ca_topic_score_gemma":3.322689e-7,"domain_scores_codex":[0.9982128,0.0008537414,0.0004730719,0.0001346725,0.0001782996,0.0001473811],"domain_scores_gemma":[0.9991834,0.00007300806,0.0003771641,0.0001163446,0.0001902271,0.00005982968],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.002961488,0.00008848279,0.0001701776,0.00005156912,0.0001146125,0.000193026,0.0003150449,0.000001592551,0.9245371,0.000009571739,0.00001517531,0.07154217],"study_design_scores_gemma":[0.008889377,0.005671288,0.108135,0.0001355513,0.0001021113,0.000691745,0.00002267827,0.0001085153,0.8758734,0.000003834597,0.0002747071,0.00009179501],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9955463,0.003306672,0.00005362349,0.0001159976,0.0001282179,0.0002939641,0.00001698831,0.000005260045,0.0005330184],"genre_scores_gemma":[0.9927375,0.006668695,0.00007285991,0.00003684194,0.0001826929,0.000001215787,0.00007656027,0.00001954416,0.0002041134],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1079648,"threshold_uncertainty_score":0.3996848,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02897446631828256,"score_gpt":0.2315168796832408,"score_spread":0.2025424133649582,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}