{"id":"W1981516407","doi":"10.1038/nature13415","title":"Comparative analysis of metazoan chromatin organization","year":2014,"lang":"en","type":"article","venue":"Nature","topic":"Genomics and Chromatin Dynamics","field":"Biochemistry, Genetics and Molecular Biology","cited_by":449,"is_retracted":false,"has_abstract":false,"ca_institutions":"Princess Margaret Cancer Centre","funders":"National Institute of General Medical Sciences; National Human Genome Research Institute; National Natural Science Foundation of China; National Institute of Biomedical Imaging and Bioengineering; Wellcome Trust; Howard Hughes Medical Institute; National Cancer Institute; National Institutes of Health; National Science Foundation","keywords":"Chromatin; Biology; ChIA-PET; Scaffold/matrix attachment region; Heterochromatin; Genetics; Genome; Bivalent chromatin; Nucleosome; Genomic organization; Histone; Caenorhabditis elegans; Computational biology; Chromatin remodeling; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002040799,0.0001171869,0.0001934085,0.0008393751,0.0003446182,0.0003285833,0.0003411511,0.0002773551,0.003069919],"category_scores_gemma":[0.0002955672,0.0001349448,0.000270407,0.0006373528,0.0002683027,0.0002989065,0.0003664224,0.0003023484,0.0003861506],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004372492,"about_ca_system_score_gemma":0.0002359153,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001326341,"about_ca_topic_score_gemma":0.004072408,"domain_scores_codex":[0.999886,0.0000138045,0.000006497523,0.00004007342,0.00003088729,0.00002266825],"domain_scores_gemma":[0.9998086,0.00005394446,0.00003011811,0.00004103941,0.0000306227,0.00003560825],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.0001388751,0.000009470111,0.002464674,0.00006396529,0.00001752723,0.00003928143,0.00005319351,0.0001110874,0.990837,0.0005832247,0.00003627696,0.005645515],"study_design_scores_gemma":[0.0000251629,0.0003821052,0.4005486,0.00003973385,0.0001424923,0.001441815,0.0002905089,0.002069167,0.5762889,0.0009924088,0.01776282,0.00001619058],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9884366,0.002658208,0.003968618,0.00009103332,0.00001364792,0.000009597734,0.0007739692,0.00004494703,0.004003475],"genre_scores_gemma":[0.990051,0.001184503,0.004647888,0.00006734621,0.00001283182,0.00001349836,0.001446339,0.00003637556,0.002540242],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003069919,"threshold_uncertainty_score":0.01026988,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.003351081159782391,"score_gpt":0.23540096583637,"score_spread":0.2320498846765876,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}