{"id":"W1981557743","doi":"10.1159/000068721","title":"O-Glycosylation of a Recombinant Carbohydrate-Binding Module Mutant Secreted by &lt;i&gt;Pichia pastoris&lt;/i&gt;","year":2003,"lang":"en","type":"article","venue":"Microbial Physiology","topic":"Glycosylation and Glycoproteins Research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":36,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia","funders":"","keywords":"Pichia pastoris; Glycosylation; Mannose; Glycan; Biochemistry; Carbohydrate-binding module; Chemistry; Recombinant DNA; N-linked glycosylation; Mutant; Fusion protein; Yeast; Oligosaccharide; Glycoprotein; Molecular biology; Biology; Cellulose; Cellulase; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0003440324,0.0002609056,0.000356423,0.0001377274,0.0001980054,0.00002096183,0.0002577124,0.0003859688,0.0002087289],"category_scores_gemma":[0.000233729,0.0002673249,0.0001565682,0.0002726283,0.0001902736,0.00001050575,0.000103054,0.0001786829,0.00004421602],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00007130887,"about_ca_system_score_gemma":0.0002201717,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00006074381,"about_ca_topic_score_gemma":0.0001424447,"domain_scores_codex":[0.9978106,0.0004372841,0.0004376107,0.0005727842,0.0001690652,0.0005726303],"domain_scores_gemma":[0.9989026,0.00002518436,0.000209292,0.0004825493,0.0002395651,0.0001407628],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002245704,0.0001467457,0.0000645654,0.00003054002,0.00006623967,0.000002318146,0.00006667858,0.00008734612,0.9933167,0.0009638893,0.004683412,0.0003469833],"study_design_scores_gemma":[0.001116865,0.0003895388,0.0004547042,0.00001645162,0.00001401947,0.000007294546,0.00001075689,0.00009239184,0.8175393,0.00022183,0.1798787,0.0002580969],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9963949,0.0004705004,0.0007042114,0.00008012621,0.000588935,0.0004866756,0.00007481204,0.0000227885,0.001177021],"genre_scores_gemma":[0.9966769,0.0001999808,0.000306776,0.00006737682,0.0001298477,0.00003563748,0.0007462372,0.00004396046,0.00179324],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1757774,"threshold_uncertainty_score":0.9999779,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007343969009796794,"score_gpt":0.2264479981404897,"score_spread":0.2191040291306929,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}