{"id":"W1981575054","doi":"10.1038/mt.2011.189","title":"Human MSC Suppression Correlates With Cytokine Induction of Indoleamine 2,3-Dioxygenase and Bystander M2 Macrophage Differentiation","year":2011,"lang":"en","type":"article","venue":"Molecular Therapy","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":710,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University; Jewish General Hospital","funders":"Canadian Institutes of Health Research","keywords":"Bystander effect; Indoleamine 2,3-dioxygenase; Macrophage; Cytokine; Biology; Immunology; Cell biology; Tryptophan; Genetics; In vitro","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00005017098,0.00014763,0.000142086,0.00009874098,0.0000884,0.00001761372,0.0001033506,0.00007464086,0.000146556],"category_scores_gemma":[0.00001599318,0.0001090896,0.00003474408,0.0001690418,0.0001273247,0.0001074428,0.0000250267,0.0001126853,0.000002686701],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000008788412,"about_ca_system_score_gemma":0.000007815037,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001755373,"about_ca_topic_score_gemma":0.000002719223,"domain_scores_codex":[0.9991165,0.0001022724,0.0001538809,0.0002809938,0.0001942402,0.0001521141],"domain_scores_gemma":[0.9995905,0.0000137669,0.0001138679,0.0002044857,0.00002700008,0.00005037409],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001923731,0.000175445,0.0004449834,0.00001213079,0.00001180316,0.00001956709,0.0007452125,0.000003832369,0.9957438,0.0004917998,0.00001328142,0.002145797],"study_design_scores_gemma":[0.001814193,0.0003974487,0.02080657,0.00002560357,0.000003293154,0.00001290258,0.0000827906,0.00004396239,0.9760138,0.0006295198,0.00003933825,0.0001305729],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.997506,0.0002303656,0.0015808,0.00002056978,0.00005098618,0.0002441369,0.000006976553,0.00004393789,0.0003162127],"genre_scores_gemma":[0.9995279,0.00008514493,0.00009067309,0.0001445012,0.0000102633,0.0000110716,0.000007490002,0.00002599765,0.00009692536],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.02036158,"threshold_uncertainty_score":0.4448544,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02649136202314328,"score_gpt":0.2375944766062781,"score_spread":0.2111031145831349,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}