{"id":"W1981575054","doi":"10.1038/mt.2011.189","title":"Human MSC Suppression Correlates With Cytokine Induction of Indoleamine 2,3-Dioxygenase and Bystander M2 Macrophage Differentiation","year":2011,"lang":"en","type":"article","venue":"Molecular Therapy","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":710,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University; Jewish General Hospital","funders":"Canadian Institutes of Health Research","keywords":"Bystander effect; Indoleamine 2,3-dioxygenase; Macrophage; Cytokine; Biology; Immunology; Cell biology; Tryptophan; Genetics; In vitro","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003281641,0.0001866903,0.0003154294,0.0002003305,0.00006344355,0.0002561886,0.00007092749,0.0001884737,0.002133949],"category_scores_gemma":[0.0002429195,0.00003877431,0.0001615068,0.000119981,0.000124051,0.00008184093,0.0001408844,0.0003128767,0.000479688],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00008782668,"about_ca_system_score_gemma":0.0001707703,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001866108,"about_ca_topic_score_gemma":0.0002939073,"domain_scores_codex":[0.9997877,0.00005685079,0.00001957682,0.00002863702,0.00007113488,0.0000361265],"domain_scores_gemma":[0.9997591,0.0000656495,0.000072915,0.00002598903,0.00003100013,0.00004533743],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001152719,0.0002301224,0.00215729,0.0001072884,0.00001946951,0.00007756746,0.00004325224,0.00008643386,0.9815009,0.00009532538,0.0001027203,0.0144271],"study_design_scores_gemma":[0.0001322727,0.00786112,0.02439981,0.0000336945,0.00009095303,0.0008887849,0.00006378915,0.0007440533,0.9576746,0.0001147615,0.007989709,0.000006390615],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9902353,0.004831837,0.002163634,0.00006901888,0.00002963747,0.00007288539,0.0001889516,0.00004054308,0.002368121],"genre_scores_gemma":[0.9972946,0.0007437996,0.000468795,0.00004061447,0.00001996976,0.00003750397,0.0002504975,0.00000585256,0.00113835],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002133949,"threshold_uncertainty_score":0.007138729,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02649136202314328,"score_gpt":0.2375944766062781,"score_spread":0.2111031145831349,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}