{"id":"W1981599381","doi":"10.1159/000188665","title":"Selective Killing of Leukemia and Lymphoma Cells Ectopically Expressing hCGβ by a Conjugate of Curcumin with an Antibody against hCGβ Subunit","year":2009,"lang":"en","type":"article","venue":"Oncology","topic":"Curcumin's Biomedical Applications","field":"Biochemistry, Genetics and Molecular Biology","cited_by":28,"is_retracted":false,"has_abstract":true,"ca_institutions":"Health Research Foundation","funders":"","keywords":"Curcumin; Antibody; Immunotoxin; Propidium iodide; Flow cytometry; Cancer research; Molecular biology; CD33; Biology; Immunoconjugate; Cell culture; Cancer cell; Trypan blue; Human chorionic gonadotropin; Monoclonal antibody; Cancer; Immunology; Programmed cell death; Apoptosis; Endocrinology; Cell biology; Biochemistry; CD34","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001243709,0.000147068,0.0002970253,0.00004702435,0.00005504183,0.000007309317,0.0001666249,0.0002472012,0.000006519255],"category_scores_gemma":[0.00002688354,0.0001306729,0.00003525253,0.000143205,0.00039043,0.000006511089,0.00004925128,0.00007717079,7.942285e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00004589893,"about_ca_system_score_gemma":0.0002906821,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00004701874,"about_ca_topic_score_gemma":0.00002137198,"domain_scores_codex":[0.9989538,0.00007991346,0.0002886341,0.0003498925,0.0001051617,0.0002226508],"domain_scores_gemma":[0.9992175,0.00004326682,0.0002163356,0.0002574884,0.0001403654,0.000125073],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001814825,0.0002928404,0.0005776676,0.00001805566,0.00003310956,0.000003170927,0.0001291509,0.000008552856,0.9740923,0.00007093251,0.0002286486,0.02436406],"study_design_scores_gemma":[0.001323597,0.002835832,0.002474051,0.00002891792,0.00003266584,0.00001994775,0.0001236372,0.0002316628,0.9727094,0.0001147588,0.01993617,0.0001693456],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9920462,0.0002900525,0.005899593,0.0001493147,0.00002098019,0.0001955705,0.00003896117,0.00001017114,0.001349136],"genre_scores_gemma":[0.9954293,0.0001546855,0.003763336,0.0002938041,0.00006021822,0.00001111649,0.0001967053,0.00001372162,0.00007712113],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.02419471,"threshold_uncertainty_score":0.5328684,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.005779610973083407,"score_gpt":0.2746005277779527,"score_spread":0.2688209168048693,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}