{"id":"W1981599381","doi":"10.1159/000188665","title":"Selective Killing of Leukemia and Lymphoma Cells Ectopically Expressing hCGβ by a Conjugate of Curcumin with an Antibody against hCGβ Subunit","year":2009,"lang":"en","type":"article","venue":"Oncology","topic":"Curcumin's Biomedical Applications","field":"Biochemistry, Genetics and Molecular Biology","cited_by":28,"is_retracted":false,"has_abstract":true,"ca_institutions":"Health Research Foundation","funders":"","keywords":"Curcumin; Antibody; Immunotoxin; Propidium iodide; Flow cytometry; Cancer research; Molecular biology; CD33; Biology; Immunoconjugate; Cell culture; Cancer cell; Trypan blue; Human chorionic gonadotropin; Monoclonal antibody; Cancer; Immunology; Programmed cell death; Apoptosis; Endocrinology; Cell biology; Biochemistry; CD34","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009912843,0.0002899333,0.0001559529,0.0001500387,0.00007531454,0.0001077364,0.0001749502,0.0001693856,0.000769522],"category_scores_gemma":[0.00008478145,0.00008125778,0.0002021001,0.00009652913,0.0001408319,0.0001118943,0.0001172751,0.0001922546,0.0001839234],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002924847,"about_ca_system_score_gemma":0.0002153805,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004797536,"about_ca_topic_score_gemma":0.0005722053,"domain_scores_codex":[0.9999324,0.000009888186,0.000004401212,0.00001800674,0.00001575591,0.00001954918],"domain_scores_gemma":[0.9999645,0.000007526041,0.00001054541,0.000005270565,0.000005852143,0.000006388073],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00007583723,0.00003035615,0.0001252759,0.00003341919,0.000004541195,0.00002652439,0.000004692557,0.0000714103,0.9983536,0.00003793003,0.00002162421,0.001214813],"study_design_scores_gemma":[0.00002133901,0.0004092384,0.001158485,0.000003797397,0.00001561903,0.000171198,0.000005326019,0.0004513294,0.996581,0.000008625309,0.001172472,0.0000016206],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9920036,0.001368897,0.00509645,0.00006453402,0.000017816,0.00006208083,0.00008366326,0.00005578699,0.001247085],"genre_scores_gemma":[0.9946054,0.0008121714,0.002972907,0.00002301243,0.000005769091,0.00004732547,0.0001356476,0.000008709763,0.001389032],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.000769522,"threshold_uncertainty_score":0.002574325,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.005779610973083407,"score_gpt":0.2746005277779527,"score_spread":0.2688209168048693,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}