{"id":"W1981601846","doi":"10.1016/j.smim.2009.05.006","title":"The innate immune response to DNA","year":2009,"lang":"en","type":"review","venue":"Seminars in Immunology","topic":"Immune Response and Inflammation","field":"Immunology and Microbiology","cited_by":78,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Calgary","funders":"","keywords":"AIM2; Innate immune system; TLR9; Inflammasome; Biology; DNA; Toll-Like Receptor 9; Pattern recognition receptor; Immune system; Cell biology; Receptor; Immunology; Genetics; Gene; DNA methylation","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006713136,0.001500687,0.001818019,0.001619127,0.0004154583,0.001400882,0.001285121,0.0017316,0.003926052],"category_scores_gemma":[0.0005832215,0.0004394542,0.0004586352,0.001783112,0.001591641,0.002254009,0.001295886,0.003278052,0.005534991],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0008547218,"about_ca_system_score_gemma":0.0009120053,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005672965,"about_ca_topic_score_gemma":0.001050991,"domain_scores_codex":[0.9997779,0.00003317234,0.00002823988,0.00004809262,0.00008559744,0.00002706513],"domain_scores_gemma":[0.999719,0.0001151813,0.0000398097,0.00001627399,0.00006653373,0.00004331593],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001532032,0.00006259687,0.0001128295,0.008211095,0.00004851775,0.0003173108,0.00005032784,0.0003297294,0.006890376,0.006249642,0.07820924,0.8993651],"study_design_scores_gemma":[0.00001343631,0.00003452933,0.0002314477,0.0008310972,0.00002220431,0.0006491149,0.00002882808,0.00003981471,0.0006612595,0.002167691,0.9953097,0.00001087091],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.00007693496,0.9957807,0.0003370245,0.0003766409,0.001709738,0.000005324031,0.00001360457,0.000009726497,0.001690267],"genre_scores_gemma":[0.0005575084,0.9949338,0.0002657005,0.0004695424,0.001295681,0.00001056252,0.00003678163,0.000002632356,0.002427809],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.003926052,"threshold_uncertainty_score":0.01313388,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01393118216937973,"score_gpt":0.2911240284906503,"score_spread":0.2771928463212706,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}