{"id":"W1981635214","doi":"10.1371/journal.pone.0007165","title":"Crystal Structure of the N-Acetylmannosamine Kinase Domain of GNE","year":2009,"lang":"en","type":"article","venue":"PLoS ONE","topic":"Inflammatory Myopathies and Dermatomyositis","field":"Medicine","cited_by":34,"is_retracted":false,"has_abstract":true,"ca_institutions":"Structural Genomics Consortium; University of Toronto","funders":"National Institute of General Medical Sciences; National Cancer Institute; Canadian Institutes of Health Research; Basic Energy Sciences; Knut och Alice Wallenbergs Stiftelse; Karolinska Institutet; Office of Science; Stiftelsen för Strategisk Forskning; Ontario Genomics Institute; Ontario Genomics; Genome Canada; GlaxoSmithKline; Ontario Innovation Trust; Wellcome Trust; U.S. Department of Energy","keywords":"Protein kinase domain; Crystal structure; Kinase; Domain (mathematical analysis); Chemistry; Crystallography; Biochemistry; Gene; Mathematics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00004998788,0.00009846084,0.0003315566,0.00004475361,0.00003592082,0.000003054842,0.00009441059,0.00007230373,0.0001489773],"category_scores_gemma":[0.00006030687,0.00006649364,0.00008237095,0.0001569292,0.00008618075,0.00003528091,0.00002951698,0.0001322699,0.000002163164],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001640179,"about_ca_system_score_gemma":0.00003724621,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000006024952,"about_ca_topic_score_gemma":0.000003558104,"domain_scores_codex":[0.9990942,0.00002838477,0.0002738788,0.0001029412,0.000361165,0.000139356],"domain_scores_gemma":[0.9992986,0.00002172462,0.0001328495,0.0003726789,0.0001220382,0.00005209109],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001462572,0.0004287756,0.003792109,0.0002588197,0.00006529294,0.00002310707,0.0005066276,0.000001246724,0.9928164,0.001468656,0.0003016438,0.0001910249],"study_design_scores_gemma":[0.001380739,0.0003049856,0.1177492,0.0005145744,0.0001627937,0.00004450062,0.0001538459,0.00002793158,0.8782384,0.001132297,0.0002028567,0.00008787547],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9969108,0.0002296665,0.000009898004,0.00105881,0.00002849694,0.0002425092,0.0000609397,0.00001936976,0.001439533],"genre_scores_gemma":[0.9975141,0.00001317882,0.001840034,0.0003849492,0.0001130059,9.729621e-7,0.00001212796,0.000009251071,0.0001123916],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.114578,"threshold_uncertainty_score":0.2711532,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01174834458506836,"score_gpt":0.2081487267580705,"score_spread":0.1964003821730021,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}