{"id":"W1981641346","doi":"10.1016/j.plefa.2011.04.024","title":"Control of experimental pulmonary tuberculosis depends more on immunostimulatory leukotrienes than on the absence of immunosuppressive prostaglandins","year":2011,"lang":"en","type":"article","venue":"Prostaglandins Leukotrienes and Essential Fatty Acids","topic":"Tuberculosis Research and Epidemiology","field":"Medicine","cited_by":35,"is_retracted":false,"has_abstract":false,"ca_institutions":"","funders":"National Heart, Lung, and Blood Institute; Merck Canada; Fundação de Amparo à Pesquisa do Estado de São Paulo","keywords":"Celecoxib; Immune system; Eicosanoid; Immunology; Mycobacterium tuberculosis; Lung; Interferon gamma; Pharmacology; Leukotriene; Tuberculosis; Medicine; Leukotriene B4; Prostaglandin E2; Biology; Arachidonic acid; Inflammation; Internal medicine; Enzyme; Asthma; Pathology; Biochemistry","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006828178,0.0003791073,0.000549492,0.0005008774,0.0002068626,0.0004936662,0.0002349131,0.0004555964,0.001323916],"category_scores_gemma":[0.001104249,0.0001513727,0.0001772847,0.0001919293,0.0007655181,0.0004697519,0.000236917,0.0005915527,0.0002121016],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003077137,"about_ca_system_score_gemma":0.0002976748,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003741937,"about_ca_topic_score_gemma":0.0003813668,"domain_scores_codex":[0.9993457,0.0002116902,0.00005496807,0.00009342539,0.0001398903,0.0001543534],"domain_scores_gemma":[0.9987807,0.0003619416,0.000277952,0.0002367248,0.00008856675,0.0002541957],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.006503429,0.001453676,0.009972486,0.000190586,0.00004777207,0.0002712769,0.00006108591,0.0001069489,0.9629246,0.0007136026,0.0001506124,0.01760408],"study_design_scores_gemma":[0.0008275435,0.02357392,0.2019036,0.0001263456,0.0001979243,0.002208194,0.0002595306,0.001122058,0.7643877,0.001051079,0.004303674,0.00003829266],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9928411,0.004081845,0.001089787,0.000235434,0.00005814222,0.00004428613,0.00007987567,0.00004705601,0.001522471],"genre_scores_gemma":[0.9974325,0.001121216,0.0004462046,0.00006568802,0.00005902618,0.00002500646,0.0001119078,0.000008020767,0.0007303668],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001323916,"threshold_uncertainty_score":0.004428923,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02595808171740636,"score_gpt":0.2882875600878732,"score_spread":0.2623294783704668,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}