{"id":"W1981654313","doi":"10.1016/j.bioorg.2008.08.004","title":"Mechanistic studies on PseB of pseudaminic acid biosynthesis: A UDP-N-acetylglucosamine 5-inverting 4,6-dehydratase","year":2008,"lang":"en","type":"article","venue":"Bioorganic Chemistry","topic":"Carbohydrate Chemistry and Synthesis","field":"Chemistry","cited_by":32,"is_retracted":false,"has_abstract":false,"ca_institutions":"Institute for Biological Sciences; University of British Columbia","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research","keywords":"Chemistry; Dehydratase; Biosynthesis; Biochemistry; N-Acetylglucosamine; Porphobilinogen synthase; Stereochemistry; Enzyme","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0002866871,0.00069063,0.0009542766,0.000052811,0.0003061958,0.00002246573,0.0007065119,0.0004603075,0.002727628],"category_scores_gemma":[0.002188498,0.0006787332,0.0003681782,0.0004403209,0.0004646883,0.00008911385,0.0002603477,0.000439571,0.0001120959],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003140355,"about_ca_system_score_gemma":0.000230728,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001184666,"about_ca_topic_score_gemma":0.000002220581,"domain_scores_codex":[0.9966611,0.00002983889,0.001097079,0.000953351,0.0006019645,0.0006566442],"domain_scores_gemma":[0.9970735,0.0004764012,0.0006265013,0.001343161,0.0001941785,0.0002862293],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001369083,0.0003611732,0.0001182744,0.001709854,0.0002906085,0.0001639961,0.0004041013,0.000002621988,0.9958671,0.00002296426,0.0005921511,0.0003302883],"study_design_scores_gemma":[0.0007374176,0.00003131214,0.00001000474,0.0005726322,0.0001868341,0.0002353827,0.001575761,0.00009664959,0.9954817,0.0000824517,0.0003156,0.0006741975],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9891245,0.001681017,0.00000942447,0.0001268749,0.0001088829,0.00007791442,0.0002442944,0.0002827637,0.008344318],"genre_scores_gemma":[0.9968377,0.0005678542,0.000216149,0.00006733902,0.0003977714,0.00004163476,0.0001152653,0.000105106,0.001651165],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.007713205,"threshold_uncertainty_score":0.9995664,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05306984544899618,"score_gpt":0.252943806875338,"score_spread":0.1998739614263418,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}