{"id":"W1981659289","doi":"10.1074/jbc.m200778200","title":"Role of the Proline-rich Domain of Dynamin-2 and Its Interactions with Src Homology 3 Domains during Endocytosis of the AT1 Angiotensin Receptor","year":2002,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"Cellular transport and secretion","field":"Biochemistry, Genetics and Molecular Biology","cited_by":37,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University; Montreal Neurological Institute and Hospital","funders":"","keywords":"Dynamin; Endocytosis; Amphiphysin; Cell biology; Endocytic cycle; Proto-oncogene tyrosine-protein kinase Src; SH3 domain; Receptor-mediated endocytosis; Clathrin; Biology; Angiotensin II; Chemistry; Receptor; Biochemistry; Signal transduction","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001080944,0.0001051735,0.0002272995,0.00001395937,0.00004396448,0.000002373743,0.0001938622,0.0001508828,0.00005182128],"category_scores_gemma":[0.00006191129,0.0000532608,0.0001712589,0.00009598405,0.0001964717,0.000003694806,0.00005923284,0.0001792934,1.044529e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0000115388,"about_ca_system_score_gemma":0.00002111773,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000001595589,"about_ca_topic_score_gemma":0.000003749285,"domain_scores_codex":[0.9992372,0.00005010259,0.0003682446,0.0001205439,0.0001117004,0.000112235],"domain_scores_gemma":[0.9991395,0.00002092281,0.0004786588,0.000163922,0.0001577381,0.00003920353],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002028327,0.0001080264,0.02358066,0.00003514171,0.00007985343,0.000001661264,0.00006298787,0.00001447801,0.9758391,0.000004840144,0.0000078687,0.00006254509],"study_design_scores_gemma":[0.0005023559,0.000188493,0.0269347,0.00005648675,0.00003643303,0.0002559942,0.0001423285,0.00001409192,0.9711908,0.0000281578,0.0005874173,0.00006278553],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9982156,0.00117386,0.00004428543,0.0002028705,0.00003406324,0.00007682689,0.00002366903,0.000001225498,0.0002276355],"genre_scores_gemma":[0.9992574,0.000314493,0.0002208972,0.00001167493,0.00008059249,0.000001530868,0.00001322296,0.000005673003,0.00009448265],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.004648349,"threshold_uncertainty_score":0.2171912,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008034548504317802,"score_gpt":0.196227288653241,"score_spread":0.1881927401489232,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}