{"id":"W1981659289","doi":"10.1074/jbc.m200778200","title":"Role of the Proline-rich Domain of Dynamin-2 and Its Interactions with Src Homology 3 Domains during Endocytosis of the AT1 Angiotensin Receptor","year":2002,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"Cellular transport and secretion","field":"Biochemistry, Genetics and Molecular Biology","cited_by":37,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University; Montreal Neurological Institute and Hospital","funders":"","keywords":"Dynamin; Endocytosis; Amphiphysin; Cell biology; Endocytic cycle; Proto-oncogene tyrosine-protein kinase Src; SH3 domain; Receptor-mediated endocytosis; Clathrin; Biology; Angiotensin II; Chemistry; Receptor; Biochemistry; Signal transduction","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002071461,0.0002581895,0.0001735695,0.0001132196,0.0002059954,0.0003131124,0.0001545002,0.000306703,0.0003912137],"category_scores_gemma":[0.0001124301,0.000137019,0.0002484366,0.00006302603,0.0001962728,0.000261627,0.0001856655,0.000255111,0.0001761314],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003113392,"about_ca_system_score_gemma":0.0001966214,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000383817,"about_ca_topic_score_gemma":0.0003836789,"domain_scores_codex":[0.9998897,0.00002476685,0.000008589401,0.00001863245,0.00002418879,0.00003409969],"domain_scores_gemma":[0.9999247,0.00001362782,0.00002280941,0.000005711289,0.000008954904,0.00002431309],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001462698,0.00001349359,0.0008191419,0.00004016135,0.000007236199,0.0002733833,0.00001679811,0.0001030037,0.9974511,0.0002446916,0.00002028065,0.0008643974],"study_design_scores_gemma":[0.00003710384,0.0001572518,0.03285077,0.00001045622,0.00003770302,0.002177467,0.00008764193,0.005260899,0.9567397,0.0002599116,0.002362304,0.00001863664],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9970527,0.001547664,0.0007344026,0.0000711426,0.000008516802,0.000005726631,0.00003327106,0.00001055315,0.0005359036],"genre_scores_gemma":[0.9983487,0.0005237531,0.0004102213,0.00002512706,0.000007023733,0.00000546759,0.0000608251,0.000003435518,0.0006154452],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0003912137,"threshold_uncertainty_score":0.002258956,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008034548504317802,"score_gpt":0.196227288653241,"score_spread":0.1881927401489232,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}