{"id":"W1981697007","doi":"10.1042/bsr20130099","title":"Purinergic stimulation of K+-dependent Na+/Ca2+ exchanger isoform 4 requires dual activation by PKC and CaMKII","year":2013,"lang":"en","type":"article","venue":"Bioscience Reports","topic":"Neuroscience and Neuropharmacology Research","field":"Neuroscience","cited_by":15,"is_retracted":false,"has_abstract":true,"ca_institutions":"Libin Cardiovascular Institute of Alberta; University of Calgary","funders":"Canadian Institutes of Health Research; Alberta Innovates","keywords":"Purinergic receptor; Cell biology; Protein kinase C; Stimulation; Signal transduction; Purinergic signalling; Gene isoform; Biology; P2Y receptor; Calmodulin; Sodium-calcium exchanger; Chemistry; Receptor; Biochemistry; Neuroscience; Enzyme; Adenosine receptor; Intracellular; Extracellular","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004868709,0.0001745193,0.0001900445,0.000247707,0.0003293901,0.0001206729,0.0002224655,0.00007528568,0.0001562799],"category_scores_gemma":[0.000852428,0.00014438,0.00003913386,0.0007347644,0.000781514,0.00137035,0.0002470484,0.0001631867,0.00001839484],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00004276958,"about_ca_system_score_gemma":0.000114887,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001195119,"about_ca_topic_score_gemma":0.00000124409,"domain_scores_codex":[0.9971362,0.0001166332,0.0004487245,0.0008447635,0.0009445053,0.0005092089],"domain_scores_gemma":[0.9987931,0.0002033962,0.0003502982,0.0003392237,0.0001085032,0.0002054673],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00001069373,0.00009725102,0.00304928,0.00001549565,6.438614e-7,0.00008013433,0.00007624366,0.00001777623,0.9938423,0.0000506693,0.0007619339,0.001997557],"study_design_scores_gemma":[0.0001640956,0.0002284283,0.01502155,0.00001199744,0.000003790838,0.0002846984,0.00002683926,0.001414061,0.9820334,0.0001723844,0.0004906781,0.0001480876],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.997567,0.000027066,0.00006202173,0.0007285232,0.0004443198,0.0006041237,0.000005209386,0.00005930618,0.0005024525],"genre_scores_gemma":[0.9978657,0.0001443902,0.00001897368,0.0004920975,0.00003770527,0.00005900423,8.911882e-7,0.0000133145,0.001367912],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01197227,"threshold_uncertainty_score":0.5887646,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04698888621055828,"score_gpt":0.3242451591850443,"score_spread":0.277256272974486,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}