{"id":"W1981697007","doi":"10.1042/bsr20130099","title":"Purinergic stimulation of K+-dependent Na+/Ca2+ exchanger isoform 4 requires dual activation by PKC and CaMKII","year":2013,"lang":"en","type":"article","venue":"Bioscience Reports","topic":"Neuroscience and Neuropharmacology Research","field":"Neuroscience","cited_by":15,"is_retracted":false,"has_abstract":true,"ca_institutions":"Libin Cardiovascular Institute of Alberta; University of Calgary","funders":"Canadian Institutes of Health Research; Alberta Innovates","keywords":"Purinergic receptor; Cell biology; Protein kinase C; Stimulation; Signal transduction; Purinergic signalling; Gene isoform; Biology; P2Y receptor; Calmodulin; Sodium-calcium exchanger; Chemistry; Receptor; Biochemistry; Neuroscience; Enzyme; Adenosine receptor; Intracellular; Extracellular","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001227059,0.0002263396,0.0002401219,0.000105939,0.000169732,0.0002839419,0.0002563946,0.0002060636,0.001356963],"category_scores_gemma":[0.0001319782,0.0001484674,0.0002415281,0.00009821153,0.000236858,0.0003579258,0.0002730208,0.0004026038,0.0002856135],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003058786,"about_ca_system_score_gemma":0.0002023796,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004856722,"about_ca_topic_score_gemma":0.001021018,"domain_scores_codex":[0.999866,0.00001970776,0.00001473677,0.00002564058,0.00003227078,0.00004153336],"domain_scores_gemma":[0.9999452,0.00001032247,0.00001730056,0.000008229383,0.000006426126,0.00001254996],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002222641,0.00002130317,0.0002339647,0.00003611684,0.000005600272,0.00006895962,0.0000121184,0.00002857415,0.9980202,0.0001075712,0.00002155463,0.001221844],"study_design_scores_gemma":[0.00006186744,0.0002124509,0.01856149,0.00001154642,0.00002442975,0.0002772188,0.00005168671,0.001431378,0.9770308,0.0001913208,0.002137333,0.000008586613],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9943335,0.001898555,0.0016564,0.0001236041,0.00004290087,0.00002684389,0.0001422705,0.00002569006,0.001750247],"genre_scores_gemma":[0.993723,0.001350231,0.002025054,0.00004248157,0.00001650953,0.00005382689,0.0002547535,0.000008354504,0.002525875],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001356963,"threshold_uncertainty_score":0.00453949,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04698888621055828,"score_gpt":0.3242451591850443,"score_spread":0.277256272974486,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}