{"id":"W1981711813","doi":"10.2165/00023210-200620010-00003","title":"Polytherapy in Bipolar Disorder","year":2006,"lang":"en","type":"review","venue":"CNS Drugs","topic":"Bipolar Disorder and Treatment","field":"Medicine","cited_by":92,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of British Columbia","funders":"H. Lundbeck A/S; Eli Lilly and Company","keywords":"Bipolar disorder; Lamotrigine; Lithium (medication); Olanzapine; Treatment of bipolar disorder; Mania; Mood stabilizer; Quetiapine; Psychiatry; Psychology; Polypharmacy; Antipsychotic; Medicine; Atypical antipsychotic; Bipolar I disorder; Antidepressant; Mood; Fluoxetine; Internal medicine; Schizophrenia (object-oriented programming); Epilepsy; Anxiety","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00009849653,0.0004479034,0.001538741,0.0003552601,0.00004013351,0.00001694707,0.0001257007,0.0002779957,0.0002013703],"category_scores_gemma":[0.000006786043,0.0003244556,0.0005485357,0.0004778561,0.00005288796,0.00003126645,0.00003319214,0.000444428,0.0003964648],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001849692,"about_ca_system_score_gemma":0.000274498,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004176537,"about_ca_topic_score_gemma":0.000274338,"domain_scores_codex":[0.9984541,0.00007574713,0.0004717562,0.0004221351,0.000211323,0.0003649518],"domain_scores_gemma":[0.9991899,0.00005125894,0.0001116056,0.00052927,0.00001894268,0.00009906461],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.000004189259,0.0004639513,0.001870621,0.003755728,0.0001453994,0.00002389537,0.0000550025,3.011961e-8,3.391538e-8,0.0001104657,0.0004500017,0.9931207],"study_design_scores_gemma":[0.0009417621,0.00007144454,0.0005540928,0.003483337,0.0006804789,0.0000611143,0.00001207696,8.139414e-7,2.14782e-7,0.00003569952,0.9938911,0.0002678778],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.00001404031,0.9939401,0.000007316736,0.0001315925,0.0001384761,0.001017787,0.00004758066,0.00006978705,0.004633391],"genre_scores_gemma":[0.00002822914,0.9942536,0.00007382422,0.00005461823,0.0001516532,0.0001641307,0.0005498317,0.0001010238,0.004623129],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9934411,"threshold_uncertainty_score":0.9999207,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02294556742025127,"score_gpt":0.3265426349828193,"score_spread":0.303597067562568,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}