{"id":"W1981728331","doi":"10.1182/blood-2011-04-346528","title":"Noninvasive bioluminescent imaging of primary patient acute lymphoblastic leukemia: a strategy for preclinical modeling","year":2011,"lang":"en","type":"article","venue":"Blood","topic":"bioluminescence and chemiluminescence research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":55,"is_retracted":false,"has_abstract":true,"ca_institutions":"Child and Family Research Institute; University of British Columbia","funders":"National Cancer Institute","keywords":"Leukemia; Medicine; Limiting; Clinical endpoint; Minimal residual disease; Cancer research; Immunology; Oncology; Clinical trial; Pathology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001561736,0.0002143596,0.0002770019,0.00005202878,0.00006414693,0.0000130119,0.0003115897,0.0001843324,0.000009769255],"category_scores_gemma":[0.0000985888,0.0001957691,0.0002027423,0.0001066985,0.000159568,0.00001139316,0.0001772112,0.00009757528,0.000003426507],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002938557,"about_ca_system_score_gemma":0.000472961,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00004777246,"about_ca_topic_score_gemma":0.000007564496,"domain_scores_codex":[0.9983794,0.00002896491,0.0004545054,0.0004999803,0.0001857575,0.0004514111],"domain_scores_gemma":[0.9989731,0.00002305696,0.0001382669,0.0004009212,0.0003281212,0.0001364804],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003731835,0.0007895995,0.008175667,0.0001928491,0.0002072469,0.00001967682,0.0001149173,0.00003133297,0.9864621,0.0000206727,0.0001804191,0.003432305],"study_design_scores_gemma":[0.001959019,0.0008604227,0.0003181148,0.00009830817,0.0001652913,0.00007542689,0.0002125532,0.001915928,0.9939709,0.00005022027,0.00008177316,0.000292024],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9947987,0.0009059195,0.002895156,0.000014715,0.0000752362,0.0004414101,0.00006289496,0.00001524593,0.0007907252],"genre_scores_gemma":[0.9970504,0.0003573328,0.001985193,0.00007134751,0.0001610951,0.0001032446,0.0001673468,0.00003297627,0.00007106301],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.007857552,"threshold_uncertainty_score":0.798323,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04004296023512451,"score_gpt":0.2819619122061345,"score_spread":0.24191895197101,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}