{"id":"W1981728331","doi":"10.1182/blood-2011-04-346528","title":"Noninvasive bioluminescent imaging of primary patient acute lymphoblastic leukemia: a strategy for preclinical modeling","year":2011,"lang":"en","type":"article","venue":"Blood","topic":"bioluminescence and chemiluminescence research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":55,"is_retracted":false,"has_abstract":true,"ca_institutions":"Child and Family Research Institute; University of British Columbia","funders":"National Cancer Institute","keywords":"Leukemia; Medicine; Limiting; Clinical endpoint; Minimal residual disease; Cancer research; Immunology; Oncology; Clinical trial; Pathology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007561867,0.000759206,0.0004355365,0.0004092626,0.0001966803,0.0006294897,0.0005383724,0.0003987236,0.001143623],"category_scores_gemma":[0.0004397123,0.0002780556,0.0002926769,0.0002082453,0.0004747418,0.0004823345,0.0003113835,0.001358904,0.0003964092],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005827323,"about_ca_system_score_gemma":0.0004741774,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007461819,"about_ca_topic_score_gemma":0.0008673882,"domain_scores_codex":[0.9997148,0.0001242211,0.00001226752,0.00005129156,0.00006087656,0.0000365038],"domain_scores_gemma":[0.9998643,0.00004124196,0.00002909648,0.00002689415,0.00001524183,0.00002318447],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000158005,0.0001600132,0.0003458327,0.00005809096,0.0000048964,0.0000557737,0.0000351603,0.0007297706,0.9934607,0.0007407547,0.0002240103,0.004027022],"study_design_scores_gemma":[0.00004748302,0.001434449,0.001283294,0.00001199777,0.00002409845,0.0004166848,0.00003680165,0.009136293,0.9828368,0.0003817138,0.004378448,0.00001178207],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.591994,0.004404117,0.3946919,0.001159661,0.0001578473,0.0009138349,0.0009946388,0.001356899,0.004326932],"genre_scores_gemma":[0.8773937,0.004718439,0.1127421,0.0001833657,0.00004114536,0.0009127749,0.0006604342,0.0001086612,0.003239341],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001143623,"threshold_uncertainty_score":0.004228115,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04004296023512451,"score_gpt":0.2819619122061345,"score_spread":0.24191895197101,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}