{"id":"W1981812533","doi":"10.1073/pnas.1309629110","title":"Vascular endothelial growth factor-dependent spatiotemporal dual roles of placental growth factor in modulation of angiogenesis and tumor growth","year":2013,"lang":"en","type":"article","venue":"Proceedings of the National Academy of Sciences","topic":"Angiogenesis and VEGF in Cancer","field":"Biochemistry, Genetics and Molecular Biology","cited_by":71,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University Health Centre; Montreal Children's Hospital","funders":"Natural Science Foundation of Tianjin City; Karolinska Institutet; European Commission; Vetenskapsrådet; Tianjin Medical University; Swedish Cancer Foundation; Eli Lilly and Company","keywords":"Angiogenesis; Placental growth factor; Vascular endothelial growth factor; Cancer research; Neovascularization; Vascular endothelial growth factor A; Biology; Tumor progression; Growth factor; Endocrinology; Internal medicine; Cancer; Medicine; VEGF receptors; Receptor","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003063175,0.0001133692,0.0001865988,0.0001343881,0.00004949577,0.000009818633,0.0002867678,0.00009665526,0.00001327489],"category_scores_gemma":[0.0002053466,0.00008272564,0.0001138075,0.0002216886,0.0004107278,0.0000524147,0.0001291451,0.00004458786,1.79035e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001695794,"about_ca_system_score_gemma":0.00004023109,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001404759,"about_ca_topic_score_gemma":0.000001434775,"domain_scores_codex":[0.9986135,0.00001196663,0.0003668939,0.0002446797,0.000636065,0.0001268287],"domain_scores_gemma":[0.9991366,0.00002800374,0.0004306565,0.00001194337,0.000361289,0.00003154389],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00001818114,0.00003503533,0.306698,0.00005750617,0.00002132666,3.00782e-9,0.00006833687,0.00001585145,0.6921122,0.0008689201,0.00002216581,0.0000824736],"study_design_scores_gemma":[0.0001904113,0.00005503325,0.4156832,0.00002380566,0.000005468581,0.00000146423,0.00007931726,0.0001365105,0.5826405,0.001127927,0.000002765281,0.00005358897],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9989856,0.0003719471,0.000003941313,0.0001720925,0.00001478045,0.0002020015,0.0001022791,0.000001997327,0.0001453032],"genre_scores_gemma":[0.9993373,0.0001471142,0.0003863256,0.00003559482,0.00006338903,0.00001097373,0.000001335652,0.000006188393,0.00001178815],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1094717,"threshold_uncertainty_score":0.3373454,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01985462168554866,"score_gpt":0.2585772247385191,"score_spread":0.2387226030529704,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}