{"id":"W1981839990","doi":"10.1176/appi.ajp.2013.13070965","title":"Adequate Dosing for Second-Generation Antipsychotics in Establishing Treatment Resistance in Schizophrenia","year":2014,"lang":"en","type":"letter","venue":"American Journal of Psychiatry","topic":"Schizophrenia research and treatment","field":"Medicine","cited_by":6,"is_retracted":false,"has_abstract":false,"ca_institutions":"Centre for Addiction and Mental Health","funders":"","keywords":"Chlorpromazine; Risperidone; Antipsychotic; Dosing; Aripiprazole; Clozapine; Schizophrenia (object-oriented programming); Medicine; Psychiatry; Pharmacology; Psychology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00268004,0.000415845,0.001353722,0.000675053,0.001335487,0.001431149,0.0009472372,0.01140551,0.001469558],"category_scores_gemma":[0.02217851,0.0003274057,0.0008252646,0.0004578302,0.001196452,0.001740153,0.0005593243,0.01050235,0.0008312585],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.002650656,"about_ca_system_score_gemma":0.002065553,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001656782,"about_ca_topic_score_gemma":0.004819316,"domain_scores_codex":[0.9975062,0.001204,0.0004868761,0.0001346879,0.0004887608,0.0001796245],"domain_scores_gemma":[0.990741,0.006103612,0.0008031394,0.0002912069,0.0010518,0.00100926],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.002846545,0.0008595524,0.04592782,0.0006205497,0.0002063854,0.07476883,0.001285616,0.001304618,0.006775591,0.0089781,0.527992,0.3284344],"study_design_scores_gemma":[0.003546287,0.005814538,0.1017793,0.003889983,0.0007596623,0.1886711,0.002395622,0.01581466,0.008726536,0.04854121,0.619638,0.000423065],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"commentary","genre_gemma":"commentary","genre_scores_codex":[0.05810525,0.01005473,0.002011144,0.8976564,0.01171833,0.00008289613,0.00009012056,0.0002003004,0.02008087],"genre_scores_gemma":[0.5076285,0.006950253,0.006731619,0.4252362,0.04714132,0.0001455278,0.0001092783,0.0001146413,0.005942593],"genre_candidate":"commentary","genre_consensus":"commentary","teacher_disagreement_score":0.01140551,"threshold_uncertainty_score":0.01923198,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03069567207036771,"score_gpt":0.3106202343446455,"score_spread":0.2799245622742778,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}