{"id":"W1981875981","doi":"10.1016/s0264-410x(02)00303-1","title":"Construction and immunogenicity of a codon-optimized Entamoeba histolytica Gal-lectin-based DNA vaccine","year":2002,"lang":"en","type":"article","venue":"Vaccine","topic":"Amoebic Infections and Treatments","field":"Medicine","cited_by":33,"is_retracted":false,"has_abstract":false,"ca_institutions":"McGill University","funders":"","keywords":"Entamoeba histolytica; Immunogenicity; Lectin; DNA vaccination; Biology; Virology; Recombinant DNA; Immune system; Protein subunit; Microbiology; Antibody; C-type lectin; Molecular biology; Immunology; Gene; Immunization; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002829862,0.0004106894,0.0004174887,0.000315051,0.0002504748,0.000416594,0.0003674689,0.0004104596,0.0007827351],"category_scores_gemma":[0.0002965599,0.0002344882,0.000363643,0.0002861747,0.000301282,0.0002164933,0.0003320745,0.00110484,0.0004126555],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004893093,"about_ca_system_score_gemma":0.0003137142,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005892512,"about_ca_topic_score_gemma":0.000506963,"domain_scores_codex":[0.9997999,0.00004832374,0.00001947542,0.0000262777,0.0000495736,0.00005648314],"domain_scores_gemma":[0.9998622,0.00003359085,0.0000302428,0.00001847147,0.00002654555,0.00002884764],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001370932,0.00006790728,0.0001253164,0.00003055848,0.000007897703,0.0000408325,0.00002491662,0.0004749853,0.9977016,0.000224769,0.0000330175,0.001131078],"study_design_scores_gemma":[0.00003773183,0.000326069,0.0007517412,0.000005220455,0.00002510537,0.00009303542,0.0000317722,0.001557204,0.9944666,0.0000900534,0.002609086,0.000006398102],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9816027,0.000407156,0.01594635,0.0001455543,0.0000734955,0.0001997049,0.0004706945,0.00006965571,0.00108477],"genre_scores_gemma":[0.9818843,0.0004132338,0.01256715,0.00007945801,0.00001402107,0.00009663683,0.001714284,0.00004558284,0.003185323],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0007827351,"threshold_uncertainty_score":0.003550231,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01140672937201569,"score_gpt":0.2295834723910919,"score_spread":0.2181767430190762,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}