{"id":"W1981960353","doi":"10.2174/156652312800099607","title":"Ex Vivo Gene Therapy and Vision","year":2012,"lang":"en","type":"review","venue":"Current Gene Therapy","topic":"Retinal Development and Disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":23,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia","funders":"Canadian Institutes of Health Research","keywords":"Ex vivo; Genetic enhancement; Clinical trial; Medicine; Multiple sclerosis; Blindness; Bioinformatics; In vivo; Biology; Pathology; Gene; Immunology; Optometry; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0002458414,0.0005713605,0.0007363632,0.00009487588,0.0000991662,0.00005487999,0.0003206931,0.000335805,0.0001099825],"category_scores_gemma":[0.000005572996,0.0004241391,0.0003344356,0.0001226108,0.00008852826,0.000005764802,0.0001155569,0.000178595,0.00005154242],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001659738,"about_ca_system_score_gemma":0.0001493319,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000001712275,"about_ca_topic_score_gemma":7.042641e-7,"domain_scores_codex":[0.9982371,0.000152339,0.000410391,0.000594394,0.0001905927,0.0004151481],"domain_scores_gemma":[0.9990653,0.00001349533,0.0002348135,0.0004751738,0.00005121334,0.0001599534],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00004736722,0.0001070454,0.00004126523,0.0004190344,0.0001318923,5.541138e-7,0.00002825381,5.241535e-8,0.002983999,0.000006854799,0.001946008,0.9942877],"study_design_scores_gemma":[0.0005577963,0.0002010988,0.00004610067,0.0003219749,0.00005362683,0.00001813024,0.000002684906,3.116677e-7,0.002621828,0.00002177494,0.9956102,0.0005444624],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.004498188,0.9935598,0.0000845455,0.0000137506,0.0008247815,0.0007050359,0.00002840106,0.0000202251,0.0002652864],"genre_scores_gemma":[0.00009425735,0.997511,0.0001923965,0.00006472068,0.0007633605,0.00008788877,0.000807491,0.00008553272,0.0003933104],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9937432,"threshold_uncertainty_score":0.9998211,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.07179217953378633,"score_gpt":0.3690908774524253,"score_spread":0.2972986979186389,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}